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Links to resources from other organisations International organisations promoting the ethical care and use of laboratory animals ANZCCART (NZ) has memberships or partnerships with four international organisations that promote greater openness, or the ethical care and humane use, of animals in research, in order to learn from international best practice. AAALAC International In late September 2009, ANZCCART New Zealand was approved for membership in the Association for Assessment and Accreditation of Laboratory Animal Care international (AAALAC International). ANZCCART continues to support the mission and work of AAALAC International by serving as an AAALAC “Member Organization.” ANZCCART joins more than 75+ other prestigious scientific, professional and educational organizations from around the world that have an interest in advancing animal well-being in science. AAALAC International is the world’s largest accrediting body for animal research and education programs. Currently more than 1,175 companies, universities, hospitals, government agencies and other research institutions in 52 countries/regions have earned AAALAC accreditation, demonstrating their commitment to responsible animal care and use. These institutions volunteer to participate in AAALAC's program, in addition to complying with all applicable local and national laws that regulate animal research. Those that meet or exceed applicable standards are awarded accreditation —a mark of quality assurance recognized around the world. ANZCCART' s continued participation as an AAALAC International Member Organization demonstrates our commitment to responsible animal care and use. It's an opportunity to join with other respected organizations to communicate that excellence in animal welfare is critical to quality science and education. For more information on AAALAC visit www.aaalac.org . International Council for Laboratory Animal Science In 2005, ANZCCART New Zealand was approved for membership in the International Council for Laboratory Animal Science (ICLAS). ICLAS is an international scientific organisation dedicated to advancing human and animal health by promoting the ethical care and use of laboratory animals in research worldwide. European Animal Research Association In 2020, ANZCCART signed a MoU with the European Animal Research Association ( EARA ) which reflects a shared commitment to greater openness, improved communications and constructive public discourse in relation to animal research in Australia and New Zealand. Understanding Animal Research In 2020, ANZCCART became a member of Understanding Animal Research ( UAR ), which seeks to achieve a broad understanding of the humane use of animals in medical, veterinary, scientific and environmental research. There is now a UAR Oceania. The Australian and New Zealand Laboratory Animal Association In 2025, ANZCCART signed a MOU with the Australian and New Zealand Laboratory Animal Association ( ANZLAA) to promote the ethical, responsible, and transparent use of animals in research and teaching across Australia and New Zealand. ANZLAA is a professional organisation dedicated to supporting individuals involved in the care and use of animals in research and teaching. ANZLAA provides a platform for networking, professional development, and knowledge exchange among laboratory animal professionals across Australia, New Zealand, and the wider Oceania region. Feature articles This section includes a selection of external articles that are relevant to researchers, teachers and students who use animals in their work. If you know of an article that should be included in this resource bank please contact us with the full reference. Squeaky clean mice could be ruining research . Nature (2018):Apr 5;556(7699):16-18 Should research animals be named? Science (2015): Vol. 347 no. 6225 pp. 941-943 Line of attack . Science (2015): Vol. 347 no. 6225 pp. 938-940 Resource bank and recommendations on best practice ANZCCART aims to promote best practice whenever animals are used for research, testing or teaching. This resource bank contains articles, newsletters and information that will help you keep up to date with the latest developments in animal welfare. Statistical design for animal welfare. We strongly recommend the resources on designing animal experiments provided by Michael Festing . Alt web (resource database hosted by Johns Hopkins University) Animal Welfare Act 1999 (Parliamentary Council Office website) ANZCCART Conferences on animal welfare in the context of research, testing and teaching Culture of Care (A NAEAC guide for people working with animals in research, testing and teaching) (PDF, 393 kb, 6 pages) Ethical guidelines for Tertiary students in laboratory classes involving the use of animals and animal tissues (ANZCCART NZ resource, 1 page PDF) Ethical guidelines for tertiary students .pdf Download PDF • 172KB Guide to the Animal Welfare Act (Ministry of Primary Industries website) SPCA New Zealand The National Animal Ethics Advisory Committee (NAEAC) website The National Animal Welfare Committee (NAWAC) website

ANZCCART Resources ComPass Animal Welfare Training This free online course covers the Australian Code and NZ Guide and welfare issues relating to animal use in research and teaching. Successful completion of Phase one of the course and its quiz fulfills the mandated basic training needs of researchers and teachers using animals as well as members of Animal Ethics Committees (AEC) in Australia and NZ (except AEC members in Victoria who are required to complete the Animal Welfare Victoria training). The aim is to standardize and augment the training offered for animal users in research and teaching throughout Australasia by offering this free online interactive and resource-rich course to all who need this training . For the course link and more information . ANZCCART (NZ) resources and best practice Three Rs Resources The Australian and New Zealand Council for the Care of Animals in Rese arch and Te aching (ANZCCART) and the Ministry for Primary Industries have produced a series of booklet s on the a pplication of the three Rs (replacement, reduction and refinement) in the use of animals in research and teaching. Organ-on-a-chip and Organoids (replacement) (2026) Cell-based Disease Models (replacement) (2019) Computer Assisted Learning (replacement) (2021) Mannequins and Dummies (replacement) (2021) Alternatives to shellfish toxicity testing (replacement) (2018) Fireflies to the rescue (reduction) (2019) Mathematical models (reduction) (2022) Tissue sharing (reduction) (2024) Simple ingenuity (refinement) (2019) Non-Invasive Methods (refinement) (2018) Living syringes (refinement) (2018) Oil emulsified gels (refinement) (2022) Other resources Animal research saves lives (2017 ANZCCART publication) What is ANZCCART? (2017 ANZCCART flyer) Download Three Rs poster (2026 ANZCCART resource) (PDF, 6.7 MB, 1 page) ANZCCART (Australia) resources and best practice Publications and information available on the ANZCCART (AU) website on the use of animals in research, testing or teaching: ANZCCART Annual Reports ANZCCART (AU) Awards ANZCCART (AU) Publications ANZCCART (AU) Fact Sheets about animals and technical information ANZCCART (AU) Helpful links on alternatives to the use of animals in research, animal ethics and welfare, environmental enrichment, recognition and alleviation of pain, and statistics ANZCCART (AU) Resources for animal care and housing, school children, school teachers, researchers and university students Newsletters ANZCCART News (Australian website). Y ou can sign up for the ANZCCART Newsletter here .

Media Information This page provides information on recent press releases, an image database, and web resources related to the use of animals in research, testing or teaching. Press releases 21 January 2026: ANZCCART NZ responds to Ministry for Primary Industries’ release of 2024 statistics on the use of animals in research, testing and teaching 20 March 2025: ANZCCART NZ releases third annual report on Openness Agreement for animal research and teaching 20 March 2025: ANZCCART NZ responds to New Zealand's animal research statistics for 2023 10th September 2024: New animal ethics resources include Māori knowledge 17 May 2024: A good step-up in Three Rs reporting and other positive trends: 2022 New Zealand Animal Research, Testing and Teaching Statistics 8 March 2024: ANZCCART New Zealand releases second annual report on Openness Agreement for animal research and teaching 13 November 2023: New Study Reveals New Zealanders' Views on Animal Use in Scientific Research and Teaching 21 August 2023: A step forward in openness in animal research and teaching but more progress needed in Three Rs reporting: New Zealand's Animal Research Statistics of 2021 30 March 2023: ANZCCART releases first report on Openness Agreement in Animal Research and Teaching 30 May 2022: Openness on use of animals in research testing and teaching statistics 27 July 2021: Science organisations pledge openness in animal research and teaching in New Zealand 1 September 2017: New resources highlight innovative ways to replace, reduce and refine the use of animals in research Submissions 21 May 2024: Submission to the Science System Advisory Group - First Phase Pat_Cragg_ANZCCART NZ_Phase1 .pdf Download PDF • 201KB Media coverage 7 October 2025: Funding to find alternatives to animal testing 24 September 2024: Māori knowledge of animals 21 March 2024: Global initiative to make animal research more transparent turns 10 – has it worked? 13 November 2023: Attitudes towards animal testing and research in Aotearoa – Expert Reaction Image database for the use of animals in research, testing or teaching An image database featuring copyright free images of animals suitable for use in stories on animal use in testing, teaching and research is available through the Understanding Animal Use website (UK based). This website also contains a number of resources on the use of animals in research. Resources Understanding Animal Research (UK website) Animal Welfare Act 1999 (Parliamentary Council Office website) Guide to the Animal Welfare Act (Ministry for Primary Industries website) The National Animal Ethics Advisory Committee (NAEAC) website The National Animal Welfare Committee (NAWAC) website SPCA New Zealand Alt web (resource database hosted by Johns Hopkins University) Annual Report (PDF, 1.5 MB, 46 pages)

Our People New Zealand Board Members: Emeritus Professor Pat Cragg (Chair), retired, formerly University of Otago (Joined 2020) Chair of the ANZCCART New Zealand Board since April 2020. Pat is a physiologist, and from undergraduate training, a zoologist; her research area covered cardiorespiratory function and control in health and disease; her breadth of teaching is typified as a co-editor of a long-standing physiology textbook. Prior to retirement in May 2018, she held appointments at the University of Otago, for instance as Head of Department of Physiology, Associate Dean Academic Health Sciences and Acting Dean of School of Biomedical Sciences. Pat was on the University's Animal Ethics Committee for 27 years and on the ANZCCART New Zealand Board for 18 years, with four years as Deputy Chair, as well as seven years as the NZ representative on the ANZCCART Australian Board. For many years Pat was Secretary of the Physiological Society of NZ and Chair of the Scientific Committee of the Otago Medical Research Foundation (OMRF). she now Chairs the OMRF Council. From mid-April 2019 to the end of January 2022, she returned from retirement to be the Acting Deputy Vice-Chancellor Academic at the University of Otago. Ian Saldanha (Deputy Chair), Biosecurity & Animal Welfare Advisor, Cawthron Institute (Joined 2021) I have been involved in the lab animal industry for over 10 years. Before taking up a position at the Cawthron Institute in Nelson, I was the Head of the Animal facility at the Malaghan Institute in Wellington. This is where my passion for working with animals grew. During this time, I served on the executive committee for Australia New Zealand Laboratory Animal Association (ANZLAA) for a few years where I used this opportunity to support those that work in the animal science field and meet others from the industry. One of the highlights in my career was getting the opportunity to travel the world, visit other animal facilities, and gain an understanding about how they operate. Outside my profession I have a love for the outdoors in particular running. I enjoy travelling, meeting new people, and of course spending time with my family. Dr Arnja Dale, Chief Scientific Officer, Royal New Zealand SPCA (Joined 2016) Arnja has over 20 years working in the field of animal welfare science in New Zealand and overseas. Arnja is the Chief Scientific Officer at SPCA New Zealand. Prior to joining SPCA, Arnja was a Senior Lecturer in Animal Welfare Science, Ethics and Law, leading numerous research projects, and also led the animal welfare investigations training programme at Unitec. She is a current member of the ANZCCART NZ, the National Animal Welfare Advisory Committee (NAWAC) and the National Animal Ethics Advisory Committee (NAEAC). Arnja is passionate about animal welfare science and changing the hearts and minds of the next generation through evidence-based education initiatives. Arnja lives in Auckland with her husband, 3 children, and her dog and cat.. Susan Doohan, Animal Welfare Officer, AgResearch (Joined 2024) Susan Doohan is a Massey trained veterinarian working as an Animal Welfare Officer based at AgResearch Grasslands Campus for the last 7 years. From an initial background in mixed practice, with a later focus on dairy cattle production, she enjoys getting to interact with inspiring research on a daily basis. Further education has included Massey postgraduate courses, and gaining Australian and New Zealand College of Veterinary Scientists membership in Animal Welfare in 2021. Working with technicians, farm staff, and scientists from varied backgrounds and skill levels, to train them to perform research and husbandry manipulations on production species, is a strong area of interest, alongside implementation of the 3R’s. Dr Nadia Mitchell, Senior Lecturer, Department of Agricultural Sciences, Lincoln University (Joined 2025) I am a neuroscientist at Lincoln University, where I lead the ovine Batten disease research programme. My research explores translational brain- and eye-directed gene therapies in sheep, and preclinical data from my laboratory has led to the FDA clearance of two gene therapy products and supported human clinical trials for CLN5 Batten disease and Frontotemporal Dementia in collaboration with industry partners. I am a passionate advocate for sustainable and ethical animal research and as an educator, my role is to instil a deep understanding of, and commitment to, animal welfare practices in research and applied farming settings. Outside of work, I love to run, walk and explore Aotearoa New Zealand with my friends and family. Dr Mike Pankhurst, Senior Lecturer, Department of Anatomy, University of Otago (Joined 2024) Mike is reproductive biologist who specialises in the biology of the ovary and female infertility. Mike began research with animals nearly 20 years ago at the University of Tasmania during his PhD studies examining tissue repair following brain injury. Since 2011, Dr Pankhurst has been investigating female reproduction and fertility at the University of Otago, initially as a postdoctoral fellow and now as Senior Lecturer in the Department of Anatomy. Mike’s research team conducts experiments with mouse models but also makes use of alternative techniques such as human (blood) samples, tissue discarded from abattoirs, mathematical models, cell culture, protein-based research and re-analysis of historic archived tissues (microscope slides) using new technologies. Mike is passionate about using a broad range of techniques because this helps to reduce the number of experiments involving animals but also increases the breadth of knowledge gained by research. Mike is the former chair of the Animal Users Group, and a current member of the Animal Practices and Compliances Steering Group, at the University of Otago. Stacey Parbhu, Animal Welfare Science Manager, Ministry for Primary Industries (Joined 2023) Stacey is currently leading the Animal Welfare systems team at MPI. As part of this role, she works alongside the National Animal Ethics Advisory Committee (NAEAC) and a team of technical and science advisors to ensure good governance to support RTT activities across New Zealand. She has been active in the care of companion animals, research animal husbandry, animal project management and animal facility management in a variety of positions since 2007, including AgResearch and Massey University. In 2017, Stacey moved to Te Herenga Waka | Victoria University in Wellington, to operate their brand-new small animal facility, eventually becoming the facility manager. In 2024 Stacey finalised her master’s thesis which utilised a mouse IVF model, providing her a greater understanding of the challenges and complexities many organisations will encounter with animal replacement techniques ANZCCART Fellow (observer) - vacant The ANZCCART Fellow is an ANZCCART board observer position for early stage researchers, to both give early stage researchers an opportunity for ANZCCART board experience, but also to inform the Board with their perspectives. Previous ANZCCART Fellows were: 2023-2025: Morgan Heslop, doctoral student, Massey University 2021-2023: Essie Van Zuylen, Postdoctoral Researcher, University of Canterbury ANZCCART NZ EXECUTIVE OFFICER Dr Marc Rands I was born in Lower Hutt and my father was a pākehā and my mother Canadian. My family moved to the UK when I was eight, and I was schooled in London, before completing a degree in Marine and Environmental Biology at the University of St. Andrews in Scotland, and a doctorate from the University of Oxford (Linacre College) studying sea anemones with symbiotic algae. I met my wife at university in Scotland, and we lived in Perth (Scotland) with our two sons while undertaking work at the Institute of Aquaculture at the University of Stirling, then working at the Scottish Higher Education Funding Council in Edinburgh, before moving to the Royal Society of Edinburgh in 1998. In 2010, I took up a position at the Royal Society of New Zealand, where I worked on supporting the Society’s expert advice, and then supporting the Society's Academy. As the ANZCCART NZ Executive Officer, I work with the Board supporting the responsible use of animals in research and teaching.

About Us About Us ANZCCART (Australian and New Zealand Council for the Care of Animals in Research and Teaching) is two independent organisations in each of Australia and New Zealand committed to providing leadership in addressing ethical, social, cultural and scientific issues relating to the use and welfare of animals in research and teaching. We have a shared Vision, Mission and Role in society. ANZCCART’s VISION To be the leading source of information and advice concerning the ethical, social, cultural and scientific use of animals in research and teaching. MISSION STATEMENT ANZCCART’s corporate mission and objectives are to promote: Informed open discussion and debate within the community when considering ethical, social, cultural and scientific issues relating to the use of animals in research and teaching, by providing a neutral forum. Excellence in the use and welfare of animals supplied for or used in research and teaching. Responsible scientific use of animals. The 3Rs principle of Replacement, Reduction and Refinement as they apply to the use of animals for scientific purposes. Strategic partnerships to contribute to the education and training of scientists, students, animal care staff, members of Animal Ethics Committees, and the broader community. ANZCCART’s ROLE ANZCCART seeks to achieve these objectives, first by providing an ongoing focus to the social, ethical, cultural and scientific issues involved, second by providing a forum for discussion of these issues and third by facilitating access to relevant specialist advice and resources. Further, through its publications and activities ANZCCART is a source of information for the general public about how animals are used in research and teaching in Australia and New Zealand. ANZCCART New Zealand Established as a standing committee of the Royal Society Te Apārangi, the Board of ANZCCART New Zealand comprises representatives from the research, animal welfare, animal ethics and education communities. ANZCCART New Zealand is an advisory organisation that provides guidance and information to a wide range of stakeholders, including Animal Ethics Committees (AEC), scientists, teachers, regulatory authorities, granting agencies, government, animal welfare organisations, the media, and the general public. ANZCCART New Zealand promotes and supports the commitment to the principles embodied in the New Zealand legislation regulating the use of animals in research, testing and teaching in New Zealand ( Animal Welfare Act 1999, Part 6 ). AIMS Our primary aims are to: Promote open discussions around the social license for, ethical and cultural considerations related to, and scientific validity of the use of animals in research and teaching. A pillar of this is the ANZCCART Openness Agreement on Animal Use in Research and Teaching. Encourage the highest standards of care, consideration and responsible use of animals for research and teaching purposes. . Act as a focal point for information and advice concerning the ethical and scientific use of animals in research and teaching. Advocate for the "Three Rs" – replacement, reduction and refinement of animals in research and teaching – as a guiding principle. Identify, enable, and enhance strategic partnerships that develop capacity by contributing to and supporting the education and training of scientists, students, and the broader community. Support the development and inclusion of mātauranga Māori in relation to the care and use of animals in research and teaching, and alignment of policy and practice with the principles of Te Tiriti o Waitangi. VALUES In pursuing our aims, we are guided by the following values: Rigour: We apply rigorous standards to our discussions and recommendations, ensuring that they are based on the best available evidence and informed by the perspectives of all relevant stakeholders. Openness: We are committed to transparency and openness in our processes, fostering an environment where challenging and informed debate can take place. Responsiveness: We aim to respond effectively to emerging ethical, social, cultural, scientific issues and developments relating to the use and welfare of animals in research and teaching. Inclusiveness: We actively engage with diverse stakeholders, including the research, animal welfare, and education communities, to ensure that our work is comprehensive and well-rounded. Collaboration: We work collaboratively with various organisations, institutions, and individuals to achieve our objectives and contribute to a more responsible and compassionate future for both animals and humans. Partnership: We support and affirm the principles of Te Tiriti o Waitangi, including the bicultural partnership it establishes between tangata Tiriti and tangata whenua, in all our aims and work. History of ANZCCART ANZCCART, the Australian and New Zealand Council for the Care of Animals in Research and Teaching, was established on the 1st of January, 1993, as a result of a collaborative effort between the Australian Council for the Care of Animals in Research and Teaching (ACCART, established in May 1987) and various New Zealand authorities, including the Ministry of Agriculture and Fisheries (now known as the Ministry for Primary Industries) and the Royal Society of New Zealand (now Royal Society Te Apārangi). In New Zealand, this followed decades of efforts by the Society to promote and progress the humane use of animals in science. The Australia-New Zealand collaboration aimed to address the growing need for ethical and scientific guidance in the use of animals for research and teaching purposes in both countries. In New Zealand, ANZCCART operates as a committee of the Royal Society Te Apārangi, maintaining strong connections with its Australian counterpart. New Zealand formed a standing committee of the Royal Society and joined ACCART to form ANZCCART in 1993. The joint name was to emphasise united efforts in promoting the ethical use of animals in research and teaching across both nations.This partnership has allowed the organizations to share resources, expertise, and knowledge while working towards common goals. For a comprehensive understanding of ANZCCART's history, we recommend reading the article “ Reflections on the use of animals in research, testing and teaching in New Zealand – a historical perspective. ” by Dr David Bayvel et al. (2011). (PDF, 653 kb, 4 pages) This article offers valuable insights into the development of ANZCCART and the progress made over the years in improving the ethical and scientific use of animals in research, testing, and teaching in both Australia and New Zealand.

ANZCCART Conference 2011 Science with feeling: animals and people Proceedings of the 2011 ANZCCART Conference Rotorua, New Zealand Contents and Foreword Opening Address Reflections on the use of animals in research, testing and teaching in New Zealand – a historical perspective – Dr A. C. David Bayvel, Linda Carsons, Paula Lemow and Dr Mark Fisher International reflections: looking back over the last 20 years – Dr Judy A. MacArthur Clark Session 1: I don’t like pain but what can we do about it? What’s special about pain? – Dr John Schofield “I’ll have the fish and shrimps”: pain and analgesia in invertebrates and fish – Dr Kurt K. Sladky The recognition and relief of pain in birds – Associate Professor Brett Gartrell Analgesia in ruminants – Dr Paul Chambers Cam Reid Oration 2011: Does the fetus feel pain, and why do we care to know? Professor Laura Bennet Session 2: Resolving the dilemmas Serving on an Animal Ethics Committee – a hospital pass or a valued distinction? Dr Mark Oliver Dr Geoff Dandie Serving on an Animal Ethics Committee – the system and pot pourri of issues Who qualifies as an investigator? – Dr Erich von Dietze and Dr Ted Rohr Animal Ethics Committees: a veterinary practitioner’s point of view – Dr Tim Mather Animal welfare in a new world – Jeanette Crosado Reflections on an Animal Ethics Committee – Dr Mandy Paterson ANZCCART New Zealand Animal Care Technicians’ Awards Compassion fatigue – Debbie Chesterfield Welfare in a chronic model of cardiac disease in sheep – Linley Nisbet Session 3: The importance of people Euthanasia in the workplace – impacts on staff – Professor Peter Davie Caring for the carers: compassion fatigue and disenfranchised grief – Dr Peter Huggard Reviewing the reviews: an update on the analysis of the process of ensuring regulatory compliance in the use of animals in science in New Zealand – Dr Virginia Williams and Linda Carsons Seeking nature in the city: the implications of feeding wildlife – Associate Professor Darryl Jones Female students’ attitudes towards the use of animals in scientific research and teaching – Sally Birdsall and Dr Beverley France Student and university perspectives on animal rights and wrongs – Dr Ngaio J. Beausoleil Animal models: their role in understanding brain dysfunction – Dr Ruth M. A. Napper Session 4: Science with feeling Science with feeling: relevance of animal emotions to research, testing and teaching – Dr Jim Webster Methodologies to measure affective states in animals: a focus on cognitive approaches – Dr Else Verbeek and Dr Caroline Lee What is it like to be a rat? Providing good environments for experimental animals – Dr Emily Patterson-Kane and Professor David J. Mellor

Applying for Animal Ethics Approval This page contains information about why you need to apply for ethics approval and how you can apply. When do you need to consider applying for animal ethics approval? You need to consider applying for animal ethics approval when using animals in teaching or in an investigation or experiment when the animal is being ‘manipulated’. This means that you are changing the animal’s normal needs, like what it eats and drinks, where it lives/sleeps or things it does (like its type of toys) in some way. This type of change (manipulation) is when ethics approval is needed and is required under New Zealand’s law called the Animal Welfare Act. Ethics approval means that a special group of people, such as science teachers and animal welfare experts have reviewed the way that your scientific experiment or investigation with animal(s) is being carried out. When they review it, they check that what is planned will not harm the animal(s) and its good health is maintained. If this group thinks that what is planned will not harm the animal(s), they will grant ethics approval. Who might need to apply for animal ethics approval? Any teacher and/or science technician using or caring for animals (e.g. for a Science Fair) in a learning or class situation should check with the New Zealand Schools Animal Ethics Committee if they need approval. Any student carrying out an investigation or experiment that involves animals should check if they need approval. In New Zealand , this includes any mammal, bird, reptile, amphibian, fish, octopus, squid, crab, lobster, or crayfish, including any mammalian foetus, or any avian or reptilian pre-hatched young, that is in the last half of its period of gestation or development, but excludes any animal in the pre-natal, pre-hatched, larval, or other such developmental stage (other than those indicated previously). Marsupial pouch young are also considered animals. The Application Process If you do need to apply for animal ethics approval for a teaching activity or for your science fair project, you need to complete a form and submit it to an Animal Ethics Committee (AEC). The New Zealand Association for Science Education has their own AEC for teachers, science technicians and students who can approve your application. For more information, visit the New Zealand Schools Animal Ethics website . In general, the AEC wants to ensure that the animals that you use will be well treated and subjected to the minimal amount of harm or disruption. All manipulations must be carried out under the umbrella of the animal welfare principles of the Three Rs (replacement, reduction and refinement). When you are writing your animal ethics application, make sure you outline the benefits of carrying out the experiment or investigation and also fully consider the harm to the animal(s). The AEC will make a risk-benefit assessment. This means that if the risk of harm to the animals high (for example, the experiment is quite invasive) then the benefits must also be high (for example, the potential of a new medicine). However, if the risk is low (for example, playing music to your fish) then the potential benefit does not need to be very high (for example, it might help you and your class better understand how well fish hear). You also need to meet the normal husbandry requirements for the animal including providing food, shelter, warmth, safety and room to behave normally. Lastly, you need to show that you have considered the Three Rs animal welfare principles in the design of your experiment or investigation. Links: Ethical guidelines for secondary school students_final .pdf Download PDF • 134KB NZ Association of Science Educators (NZASE) website on animal ethics

Resources ANZCCART has a variety of resources available for teachers and students to learn about ways that animals are used in research, testing and teaching. Teaching and learning about Māori knowledge of animals and how Māori concepts can inform animal ethics Open-access digital resources are available on the Science Learning Hub – Pokapū Akoranga Pūtaiao: · Māori knowledge of animals ; · Māori concepts for animal ethics . A Māori medium e-version is also available to download. A te reo Māori version (2024) for use in kura is available to download here: Roy 180 Compositestudent_Digital .pdf Download PDF • 7.63MB The resources are written by Professor Georgina Tuari Stewart, a Pūtaiao education expert from AUT, and Associate Professor Sally Birdsall, a primary science teacher educator and academic from University of Auckland. Caring for the animals we use in research and teaching ANZCCART has produced a resource called “Caring for the animals we use in research and teaching” (2015). The centrepiece of this resource is a DVD which provides a series of interviews with scientists who use animals in their research. This DVD is an excellent resource for generating class discussion and debate around the use of animals in research and teaching. The research topics discussed on the DVD are: research into developing anti-cancer drugs (presented by Professor Bill Wilson); genetic causes for obesity (presented by Dr Kathy Mountjoy); the effects of pre-natal nutrition on lambs (presented by Professor Jane Harding); the use of pain relief on farms for procedures such as castration and docking of lambs’ tails (presented by Dr Craig Johnson); the effects of the gene kisspeptin on puberty and fertility (presented by Professor Allan Herbison); development of the Xcluder Pest Proof Fence which is in use at Maungatautari (presented by Dr Tim Day); legislation governing the use of animals in research and teaching (presented by Professor Don Love and Dr Sally Birdsall). The video clips from the DVD can be downloaded by teachers from the following web link . A password will be required and will be available upon request to teachers ( contact ANZCCART NZ ). A compilation of interviews on these topics, narrated by Dr Jessie Jacobsen, the 2007 MacDiarmid Young Scientist of the Year (now called the Prime Minister’s MacDiarmid Emerging Scientist of the year), is also available. A set of activities has been developed to accompany each of the interviews for Years 9-10 students. They are designed to encourage discussion about the ways in which animals are used in research, as well as having a literacy focus. Each set of activities has links to the Nature of Science strand and to relevant contextual strands in the revised New Zealand school curriculum together with suggested ways of developing relevant key competencies. If you would like a copy of the DVD, please contact ANZCCART NZ . Assessment Resources ANZCCART (NZ) has supported the development of three NCEA assessment tasks that have received the Quality Assured Assessment materials trade mark (QAAM) from the NZQA for NCEA Achievement Standards (Biology 2.2, and 3.2), which integrates biological knowledge to develop an informed response to a socio-scientific issue in 2019. The three resources are: Biology 2.2 (AS 91154) Animal research: The best thing for human medicine and animals? – NCEA Level 2 – Internal Assessment Resource Biology 3.2 (AS 91602) Animal research: The ethics of using animals for research and teaching in New Zealand – NCEA Level 3 – Internal Assessment Resource Biology 3.2 (AS 91602) Animal research: Predator proof fences – NCEA Level 3 – Internal Assessment Resource Each of the tasks is available as a ‘ready to use’ package and contains: The achievement standard Teacher guidelines for and conditions of assessment The assessment task The assessment schedule Planning notes for teachers and suggested resources These teaching resources are not available on-line, but can be sent to teachers upon request ( contact ANZCCART NZ ). A 2019 student resource to accompany these tasks, Using Animals in Science: Student Resource, is available to download here . Three Rs Booklets A series of booklets have been produced that illustrate how the Three Rs are being used in scientific research. Organ-on-a-Chip and Organoids (replacement) (2026) Organ on a chip and organoids-compressed .pdf Download PDF • 12.71MB Cell-based Disease Models (replacement) (2019) Computer Assisted Learning (replacement) (2021) Mannequins and Dummies (replacement) (2021) Alternatives to shellfish toxicity testing (replacement) (2018) Fireflies to the rescue (reduction) (2019) Mathematical models (reduction) (2022) Tissue sharing (reduction) (2024) Simple ingenuity (refinement) (2019) Non-Invasive Methods (refinement) (2018) Living syringes (refinement) (2018) Oil emulsified gels (refinement) (2022) Links to Other Resources Other resources are also available here: Using animals in science , student resource (2019 ANZCCART publication) (PDF, 2.8 MB, 22 pages) Animal research saves lives, questions and answers (2017 ANZCCART resource) (PDF, 1.8 MB, 14 pages) Animal ethics resources on TKI website DEMOCS discussion game (from EdinEthics, UK website) SPCA New Zealand Culture of Care (NAEAC guide for people working with animals in research, testing and teaching) (PDF) Animal Welfare Act 1999 Part 6 ANZCCART 3Rs poster .pdf Download PDF • 8.53MB Three Rs resources (ANZCCART pages) Johns Hopkins CAAT page The National Animal Ethics Advisory Committee (NAEAC) website The National Animal Welfare Committee (NAWAC) website

Information on Animal Research in New Zealand for Schools It is the responsibility of everyone who uses animals to ensure that they are only used when absolutely necessary and that when they are used they are treated with care and respect. If an animal is used for research, testing or teaching the work must be conducted in line with the Three Rs (from the ideas of Russell and Burch in their 1959 book “The principles of humane experimental technique”, available through the Johns Hopkins Alt Web website): Replacement : where possible an alternative to animal testing must be used. This could include a computer model or cell culture (where animal or human cells are grown in a laboratory). Reduction : the minimum number of animals must be used to gain good experimental results. This means that experiments must be well designed and that as many experimental variables as possible are controlled (i.e. that you only change one thing in your experimental group as compared to your control group). This means that the research or test will provide quality data which can withstand statistical analysis. Refinement : the animals should not suffer. At all times the health and well-being of the animal should be a priority. As much as possible the animal should be able to live normally, free from any pain and suffering, throughout the research, teaching or testing process. ANZCCART booklets providing examples of how these principles have been applied are available here . Resources on the use of animals in research, testing or teaching for schools The following resources are available on the use of animals in research, testing or teaching: Using animals in science , student resource (ANZCCART publication 2019) (PDF, 2.8 MB, 22 pages) Animal research saves lives, questions and answers (ANZCCART resource 2013) (PDF, 1.8 MB, 14 pages) Download Three Rs poster (ANZCCART resource) (PDF, 6.7 MB, 1 page) Animal welfare in NZ (Ministry for Primary Industries) National Animal Ethics Advisory Committee (NAEAC) website National Animal Welfare Advisory Committee (NAWAC) website Alt web (resource database hosted by Johns Hopkins University) SPCA New Zealand Animal ethics resources on TKI website DEMOCs discussion game (from EdinEthics, UK Website)

ComPass Animal Welfare Training This free online course covers the Australian Code and NZ Animal Welfare Act 1999. Successful completion of Phase one of the course and its quiz fulfills the mandated basic training needs of researchers and teachers using animals as well as members of Animal Ethics Committees (AEC) in Australia and NZ (except AEC members in Victoria who are required to complete the Animal Welfare Victoria training). The aim is to standardize and augment the training offered for animal users in research and teaching throughout Australasia by offering this free online interactive and resource-rich course to all who need this training. For the course link and more information (Australian website) .

The Three Rs Animal Welfare Principles for research, testing and teaching The Three Rs — replacement, reduction and refinement — were first introduced by the authors Russell and Burch in their 1959 book, The Principles of Humane Experimental Technique (available through the Johns Hopkins Alt Web website and the abridged version on the norecopa website ). Since then these ideas have become fundamental principles in the area of animal welfare for research, testing and teaching. Replacement Accelerating the development and use of predictive and robust models and tools, based on the latest science and technologies, to replace the use of animals in addressing important research questions where they would have otherwise been used. Reduction Appropriately designed and analysed animal experiments that are robust and reproducible, and add to the knowledge base. Refinement Advancing laboratory animal welfare by exploiting the latest in vivo technologies to minimise pain, suffering and distress and improve understanding of the impact of welfare on scientific outcomes. Booklets outlining examples of the application of these principles can be found here .

Animal welfare What is animal welfare and whose welfare is considered? Animals are recognized as sentient beings in New Zealand law. This means they have sufficiently complex nervous systems to support flexible and adaptive behaviour and, importantly, a range of different experiences and feelings that they can interpret as good/positive or bad/negative. In New Zealand, animals considered to be sentient are mammals, birds, reptiles, amphibians, fish, octopus, squid, crabs, lobsters and crayfish (see Information about animal research in NZ for more information). The welfare of an animal depends on its mental state – the negative or positive experiences it is having at a particular point in time. Negative experiences might include pain, discomfort, breathlessness, nausea, fear, anxiety, hunger, thirst and even loneliness, frustration or boredom, depending on the kind of animal. Good experiences might include feelings of pleasure, comfort, safety and companionship, again depending on the kind of animal. The animal’s mental state is influenced by its perception of both its physical health and its environment. How can we understand an animal’s welfare state to make improvements? Often in research, it is necessary to perform procedures that may cause animals to experience negative states like fear, pain, nausea, or breathlessness. In addition to compromise during procedures, animals may also experience compromise in their home environment, during day-to-day husbandry and handling, preparation for, as well as recovery from, the procedure. An animal may be more likely to experience welfare compromise because of its age, physical state, particular type or breeding. When using animals in research, testing, and teaching, we have a responsibility to promote good welfare, meaning minimizing welfare compromise due to negative experiences and enhancing welfare by providing opportunities for positive experiences. The people responsible must consider the ways that their use of, or interaction with, the animals may impact their welfare. Another way to think about this is to ask “What mental states will the animal experience in this situation, in this physical condition or due to this procedure?”. We can understand the degree to which welfare is compromised by evaluating the quality, likelihood, severity/intensity and duration of any and all negative experiences; we do this using observable or measurable indicators of mental states, including behavioural, physiological and neurophysiological measurements. Likewise, we can understand the degree of welfare enhancement, primarily by evaluating animal’s behavioural responses to opportunities that arise or we provide. One model we can use to organize investigations of welfare and the evidence for an animal’s mental experiences and its overall welfare state is the Five Domains Model. This is an internationally recognised welfare assessment framework developed in New Zealand. It reflects modern understanding of animal welfare by breaking down the factors that influence welfare into four categories (Domain 1 Food and water; Domain 2 Physical environment; Domain 3 Health and physical status; Domain 4 Behavioural interactions) and includes the associated mental experiences in a fifth category (Domain 5 Mental states). With care, the Model can be used for any species in any context. It allows the user to apply their own knowledge of the animal species to identify potential sources of welfare compromise and opportunities for welfare enhancement. How can we improve the welfare of animals used in RTT? The Three Rs The Three Rs provide guidance on ways to minimize welfare compromise for animals used in RTT by avoiding animal use altogether (Replacement), reducing the number of animals that might experience welfare compromise whilst still achieving the purpose of having used them (Reduction) or reducing the likelihood, severity and/or duration of negative mental experiences arising due to the ways animals are used and managed (Refinement). Providing opportunities for positive experiences, while continuing to minimise negatives, is another way to refine animal use. For more information about the Three Rs see NC3Rs . Minimizing welfare compromise (Refinement) depends on what the problem is for the animal. Importantly, animals must be conscious to be having any mental experiences, including pain, so using general anaesthesia to make an animal unconscious is one way to reduce welfare compromise during a procedure. Pain can also be alleviated or reduced by using drugs that block or reduce pain signals (local anaesthetics or analgesics). However, pain-relieving drugs won’t reduce hunger, thirst, breathlessness, nausea, fear or loneliness. So, the remedy must be appropriate for the problem, and the effectiveness of the intervention should be evaluated using methods like those described above. For example, fear due to human-animal interactions can be reduced by avoiding or refining handling procedures, while anxiety might be relieved by manipulating animal housing or social groupings. Likewise, such changes in animal housing and management can provide animals opportunities for positive experiences. Promoting these feelings wherever possible can enhance the welfare of animals, as well as making them easier to handle and work with. Resources for minimizing welfare compromise: Beausoleil, N., & Mellor, D. (2015). Introducing breathlessness as a significant animal welfare issue. New Zealand Veterinary Journal , 63 (1), 44–51. https://doi.org/10.1080/00480169.2014.940410 Resources for enhancing welfare: ·Baumans, V. (2005). Environmental Enrichment for Laboratory Rodents and Rabbits: Requirements of Rodents, Rabbits, and Research. ILAR Journal , 46 (2), 162–170. https://doi.org/10.1093/ilar.46.2.162 Rault, J.-L., Waiblinger, S., Boivin, X., & Hemsworth, P. (2020). The Power of a Positive Human–Animal Relationship for Animal Welfare. Frontiers in Veterinary Science , 7 . https://www.frontiersin.org/articles/10.3389/fvets.2020.590867 Resources for understanding animal welfare and its assessment: Mellor, D. J. (2017). Operational Details of the Five Domains Model and Its Key Applications to the Assessment and Management of Animal Welfare. Animals, 7(8), Article 8. https://doi.org/10.3390/ani7080060 Mellor, D. J., Beausoleil, N. J., Littlewood, K. E., McLean, A. N., McGreevy, P. D., Jones, B., & Wilkins, C. (2020). The 2020 Five Domains Model: Including Human–Animal Interactions in Assessments of Animal Welfare. Animals, 10(10), 1870. https://doi.org/10.3390/ani10101870 Littlewood, K.E.; Beausoleil, N.J.; Mellor, D.J. Updating the Five Provisions: Aligning Welfare-Focused Care with the Five Domains Model. Animals 2026 , 16 , 1927. https://doi.org/10.3390/ani16121927