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Use of Animals in New Zealand Records of the annual numbers of animals used in research, testing and teaching have been collected since 1987, and record animals that have had manipulations involving the normal physiological, behavioural, or anatomical integrity of the animal by deliberately subjecting it to a procedure which is unusual or abnormal when compared with that to which animals of that type would be subjected under normal management or practice. This can involve exposing the animal to any parasite, micro-organism, drug, chemical, biological product, radiation, electrical stimulation, or environmental condition; or enforced activity, restraint, nutrition, or surgical intervention; or depriving the animal of usual care. Proportion of animals (per type) used in research, testing and teaching in 2024 From 1 January 2018, the definition of ‘manipulation’ was expanded to include the killing of an animal for research, testing or teaching on its body or tissues, and the breeding or producing offspring that have potentially compromised welfare due to breeding (for example, to research some hereditary medical conditions). All animals reported in this new category are required to be treated with the same duty of care as animals used for research and teaching. Reasons for animals being bred but not used might include: Wrong sex for the specific research project (this is because the sex ratio of offspring can often not be controlled prior to birth). Creating or maintaining genetically altered lines (not all offspring have the required genetic alteration). Number bred was over and above what was needed (exact size of litters or number of offspring born are usually unpredictable). Sufficient numbers are needed to sustain animal colonies, as well as ensure adequate diversity and sufficient timely supply for research and teaching purposes. ‘Sentinel animals’ used for health screening of other animals in the laboratory, whose condition hints towards any subtle health issues in the lab that could widely impact other animals’ welfare. The animals can also be useful after death in teaching and training, or by storing tissues from the animals which can be used in future research. This may reduce the number of animals that need to be bred and used in future. Statistics on New Zealand’s use of animals in research can be found here: 2024 , 2023 , 2022 , 2021 , 2020 , 2019 , 2018 , 2017 , 2016 , 2015 , 2014 , 2013 , 2012 , 2011 , 2010 Infographics on this data can be found here: 2020 , 2019 , 2018 , 2017 The definition of animal, however, varies from country to country: In New Zealand it includes any mammal, bird, reptile, amphibian, fish, octopus, squid, crab, lobster, or crayfish, including any mammalian foetus, or any avian or reptilian pre-hatched young, that is in the last half of its period of gestation or development, but excludes any animal in the pre-natal, pre-hatched, larval, or other such developmental stage (other than those indicated previously). Marsupial pouch young are also considered animals. In Australia it includes any fish, amphibians, reptiles, birds, mammals and cephalopods, but with some variation by state. In some States it also extends to lobsters, crabs or crayfish. In South Australia, a license is not required to use fish for research purposes. In the US , it includes warm-blooded animals, but excludes birds, rats and mice bred for use in research. In the EU , it includes live vertebrate animals and cephalopods, including independently feeding larval forms and foetal forms of mammals.

FAQs Frequently asked questions: 1. What regulations exist for animal research in New Zealand? New Zealand law mandates that researchers must apply to an Animal Ethics Committee (AEC) to gain approval for using animals in research, testing, and teaching. These AECs are also tasked with monitoring approved research activities. The composition of AECs includes a veterinarian, a scientist, a nomination of an approved organization (e.g., SPCA), and a layperson with no involvement in animal research. This diverse membership provides a broad perspective on animal welfare. The government, while not directly involved in AEC decision-making, regulates animal research by reviewing the codes of ethical conduct that AECs and researchers operate under, oversees these AECs and requires annual reporting from the organisations that have them. 2. Is cosmetic testing on animals allowed in New Zealand? Testing on animals for developing, making, or testing a cosmetic or an ingredient that is intended exclusively for use in a cosmetic is explicitly banned in New Zealand under the Animal Welfare Act 1999, 2015 amendment. 3. How are animals chosen for research? Animals are selected for research based on the specific needs of the study and the suitability of different species to provide relevant data. The selection process is governed by ethical considerations, aiming to use non-sentient, or non-living organisms where possible and to minimize the number of animals used. Researchers must demonstrate that no viable alternatives exist and that the potential benefits of the research justify the use of animals. 4. Are there alternatives to using animals in research? Yes, researchers actively seek alternatives to animal testing, such as cell-based models, computer modelling, and other technologies that can reduce or eliminate the need for animal use. This effort aligns with the Three Rs: Replacement of animals with non-animal methods, Reduction in the number of animals used, and Refinement of techniques to reduce impacts. 5. How can the public learn more about animal research? The public can learn more about animal research through various trusted sources, including animal welfare organizations, regulatory bodies, and research institutions. Many of these organisations support openness about use of animals in research and teaching as signatories to the Openness Agreement on Animal use in Research and Teaching in New Zealand. They provide educational resources online, offering insights into how animal research is conducted, regulated, and how it contributes to scientific and medical advancements. Engaging with these sources can provide a balanced view of the ethical considerations and the importance of animal research in certain contexts.

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< Back 2014 ANZCCART Essay Competition Winner Conversations to Improve Animal Welfare in Research and Teaching (by Katherine Reid) Previous Next

Animal welfare What is animal welfare and whose welfare is considered? Animals are recognized as sentient beings in New Zealand law. This means they have sufficiently complex nervous systems to support flexible and adaptive behaviour and, importantly, a range of different experiences and feelings that they can interpret as good/positive or bad/negative. In New Zealand, animals considered to be sentient are mammals, birds, reptiles, amphibians, fish, octopus, squid, crabs, lobsters and crayfish (see Information about animal research in NZ for more information). The welfare of an animal depends on its mental state – the negative or positive experiences it is having at a particular point in time. Negative experiences might include pain, discomfort, breathlessness, nausea, fear, anxiety, hunger, thirst and even loneliness, frustration or boredom, depending on the kind of animal. Good experiences might include feelings of pleasure, comfort, safety and companionship, again depending on the kind of animal. The animal’s mental state is influenced by its perception of both its physical health and its environment. How can we understand an animal’s welfare state to make improvements? Often in research, it is necessary to perform procedures that may cause animals to experience negative states like fear, pain, nausea, or breathlessness. In addition to compromise during procedures, animals may also experience compromise in their home environment, during day-to-day husbandry and handling, preparation for, as well as recovery from, the procedure. An animal may be more likely to experience welfare compromise because of its age, physical state, particular type or breeding. When using animals in research, testing, and teaching, we have a responsibility to promote good welfare, meaning minimizing welfare compromise due to negative experiences and enhancing welfare by providing opportunities for positive experiences. The people responsible must consider the ways that their use of, or interaction with, the animals may impact their welfare. Another way to think about this is to ask “What mental states will the animal experience in this situation, in this physical condition or due to this procedure?”. We can understand the degree to which welfare is compromised by evaluating the quality, likelihood, severity/intensity and duration of any and all negative experiences; we do this using observable or measurable indicators of mental states, including behavioural, physiological and neurophysiological measurements. Likewise, we can understand the degree of welfare enhancement, primarily by evaluating animal’s behavioural responses to opportunities that arise or we provide. One model we can use to organize investigations of welfare and the evidence for an animal’s mental experiences and its overall welfare state is the Five Domains Model. This is an internationally recognised welfare assessment framework developed in New Zealand. It reflects modern understanding of animal welfare by breaking down the factors that influence welfare into four categories (Domain 1 Food and water; Domain 2 Physical environment; Domain 3 Health and physical status; Domain 4 Behavioural interactions) and includes the associated mental experiences in a fifth category (Domain 5 Mental states). With care, the Model can be used for any species in any context. It allows the user to apply their own knowledge of the animal species to identify potential sources of welfare compromise and opportunities for welfare enhancement. How can we improve the welfare of animals used in RTT? The Three Rs The Three Rs provide guidance on ways to minimize welfare compromise for animals used in RTT by avoiding animal use altogether (Replacement), reducing the number of animals that might experience welfare compromise whilst still achieving the purpose of having used them (Reduction) or reducing the likelihood, severity and/or duration of negative mental experiences arising due to the ways animals are used and managed (Refinement). Providing opportunities for positive experiences, while continuing to minimise negatives, is another way to refine animal use. For more information about the Three Rs see NC3Rs . Minimizing welfare compromise (Refinement) depends on what the problem is for the animal. Importantly, animals must be conscious to be having any mental experiences, including pain, so using general anaesthesia to make an animal unconscious is one way to reduce welfare compromise during a procedure. Pain can also be alleviated or reduced by using drugs that block or reduce pain signals (local anaesthetics or analgesics). However, pain-relieving drugs won’t reduce hunger, thirst, breathlessness, nausea, fear or loneliness. So, the remedy must be appropriate for the problem, and the effectiveness of the intervention should be evaluated using methods like those described above. For example, fear due to human-animal interactions can be reduced by avoiding or refining handling procedures, while anxiety might be relieved by manipulating animal housing or social groupings. Likewise, such changes in animal housing and management can provide animals opportunities for positive experiences. Promoting these feelings wherever possible can enhance the welfare of animals, as well as making them easier to handle and work with. Resources for minimizing welfare compromise: Beausoleil, N., & Mellor, D. (2015). Introducing breathlessness as a significant animal welfare issue. New Zealand Veterinary Journal , 63 (1), 44–51. https://doi.org/10.1080/00480169.2014.940410 Resources for enhancing welfare: ·Baumans, V. (2005). Environmental Enrichment for Laboratory Rodents and Rabbits: Requirements of Rodents, Rabbits, and Research. ILAR Journal , 46 (2), 162–170. https://doi.org/10.1093/ilar.46.2.162 Rault, J.-L., Waiblinger, S., Boivin, X., & Hemsworth, P. (2020). The Power of a Positive Human–Animal Relationship for Animal Welfare. Frontiers in Veterinary Science , 7 . https://www.frontiersin.org/articles/10.3389/fvets.2020.590867 Resources for understanding animal welfare and its assessment: Mellor, D. J. (2017). Operational Details of the Five Domains Model and Its Key Applications to the Assessment and Management of Animal Welfare. Animals, 7(8), Article 8. https://doi.org/10.3390/ani7080060 Mellor, D. J., Beausoleil, N. J., Littlewood, K. E., McLean, A. N., McGreevy, P. D., Jones, B., & Wilkins, C. (2020). The 2020 Five Domains Model: Including Human–Animal Interactions in Assessments of Animal Welfare. Animals, 10(10), 1870. https://doi.org/10.3390/ani10101870

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