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Information about animal research in New Zealand The use of animals in research, testing and teaching in New Zealand Animal use in research, testing and teaching in New Zealand is strictly controlled under the Animal Welfare Act 1999 . Any person or organisation using animals must follow an approved code of ethical conduct, which sets out the policies and procedures that must be followed by the organisation and its animal ethics committee. Further information about the regulation of animal research is available from the Ministry for Primary Industries. It is the responsibility of everyone who uses animals to ensure that they are only used when absolutely necessary and that when they are used they are treated with care and respect. If an animal is used for research, testing or teaching the work must be conducted in line with the Three Rs (from the ideas of Russell and Burch in their 1959 book The principles of humane experimental technique available through the Johns Hopkins Alt Web website). Replacement Accelerating the development and use of predictive and robust models and tools, based on the latest science and technologies, to replace the use of animals in addressing important research questions where they would have otherwise been used. Reduction Appropriately designed and analysed animal experiments that are robust and reproducible, and add to the knowledge base. Refinement Advancing laboratory animal welfare by exploiting the latest in vivo technologies to minimise pain, suffering and distress and improve understanding of the impact of welfare on scientific outcomes. Animal use statistics Annual records of the annual numbers of animals used in research, testing and teaching have been collected and published by the Ministry for Primary Industries (MPI) since 1987 ( MPI animal use statistics ). What is recorded are animals that have had their normal physiological, behavioural, or anatomical integrity altered by a procedure (called a 'manipulation'). This can involve exposing the animal to any parasite, micro-organism, drug, chemical, biological product, radiation, electrical stimulation, or environmental condition; or enforced activity, restraint, nutrition, or surgical intervention; or depriving the animal of usual care. Further details of ‘manipulations’, annual statistics and the definition of an ‘animal’ according to the NZ Animal Welfare Act can be found below . Records of the annual numbers of animals used in research, testing and teaching have been collected since 1987, and record animals that have had manipulations involving the normal physiological, behavioural, or anatomical integrity of the animal by deliberately subjecting it to a procedure which is unusual or abnormal when compared with that to which animals of that type would be subjected under normal management or practice. This can involve exposing the animal to any parasite, micro-organism, drug, chemical, biological product, radiation, electrical stimulation, or environmental condition; or enforced activity, restraint, nutrition, or surgical intervention; or depriving the animal of usual care. Proportion of animals (per type) used in research, testing and teaching in 2024 From 1 January 2018, the definition of ‘manipulation’ was expanded to include the killing of an animal for research, testing or teaching on its body or tissues, and the breeding or producing offspring that have potentially compromised welfare due to breeding (for example, to research some hereditary medical conditions). All animals reported in these new categories are required to be treated with the same duty of care as animals used for research and teaching. From 1 January 2019 the number of animals bred but not used also had to be reported in another new category. Reasons for animals being bred but not used might include: Wrong sex for the specific research project (this is because the sex ratio of offspring can often not be controlled prior to birth). Creating or maintaining genetically altered lines (not all offspring have the required genetic alteration). Number bred was over and above what was needed (exact size of litters or number of offspring born are usually unpredictable). Sufficient numbers are needed to sustain animal colonies, as well as ensure adequate diversity and sufficient timely supply for research and teaching purposes. ‘Sentinel animals’ used for health screening of other animals in the laboratory, whose condition hints towards any subtle health issues in the lab that could widely impact other animals’ welfare. The animals can also be useful after death in teaching and training, or by storing tissues from the animals which can be used in future research. This may reduce the number of animals that need to be bred and used in future. Statistics on New Zealand’s use of animals in research: 2024 , 2023 , 2022 , 2021 , 2020 , 2019 , 2018 , 2017 , 2016 , 2015 , 2014 , 2013 , 2012 , 2011 , 2010 Infographics on this data (incorporated into reports from 2021): 2020 , 2019 , 2018 , 2017 ANZCCART NZ press releases relating to MPI statistics: 2024 , 2023 , 2022 , 2021 , 2020 The definition of animal, however, varies from country to country: In New Zealand it includes any mammal, bird, reptile, amphibian, fish, octopus, squid, crab, lobster, or crayfish, including any mammalian foetus, or any avian or reptilian pre-hatched young, that is in the last half of its period of gestation or development, but excludes any animal in the pre-natal, pre-hatched, larval, or other such developmental stage (other than those indicated previously). Marsupial pouch young are also considered animals. In Australia it includes any fish, amphibians, reptiles, birds, mammals and cephalopods, but with some variation by state. In some States it also extends to lobsters, crabs or crayfish. In South Australia, a license is not required to use fish for research purposes. In the US , it includes warm-blooded animals, but excludes birds, rats and mice bred for use in research. In the EU , it includes live vertebrate animals and cephalopods, including independently feeding larval forms and foetal forms of mammals. Institutional Codes of Ethical Conduct under animal welfare legislation Before institutions in New Zealand are permitted to use animals for research, testing or teaching, they must apply for a licence from the government. The licence is called a ‘Code of Ethical Conduct’. This system is unique to New Zealand. Each institutional Code sets out the conditions and rules for animal use and the approving procedures of its Animal Ethics Committee. Codes vary between organisations, depending upon the nature of the scientific activity. These Codes offer insights into how organisations value animals used for scientific or teaching purposes. A list of Code Holders can be found at the end of each MPI annual statistics report, including a list of organisations who have an approved arrangement to use the Code of another organisation. Since 2021 the ANZCCART New Zealand Openness Agreement has encouraged all research and teaching signatories to make the code they use publicly available on their institution’s website. New Zealanders' Attitudes to Animal Research in 2023 A recently conducted study reveals New Zealanders’ perspectives and knowledge on the use of animals in scientific research, testing, and teaching. The study was conducted on behalf of the New Zealand board of the Australian and New Zealand Council for the Care of Animals in Research and Teaching (ANZCCART NZ). You can read the report here: ANZCCART_Animal research report Final .pdf Download PDF • 3.37MB ANZCCART Press release: New Study Reveals New Zealanders' Views on Animal Use in Scientific Research and Teaching Science Media Centre expert reaction to the study can be read here . Research animal re-homing ANZCCART supports and encourages the re-homing of research animals as an alternative to euthanasia, wherever possible.

Information for New Zealand Researchers and Tertiary Education Researchers, technicians or tertiary teachers are often directly responsible for animal welfare. The following information has been designed by ANZCCART to assist these groups when they are conducting research, testing and/or undertaking teaching involving animals. Animal ethics and legislation in New Zealand Please click to follow link for information on ethics and legislation in New Zealand. Understanding Animal Ethics Committees Please click to follow link for information on Animal Ethics Committees and the criteria for assessing applications . Assistance with statistics in designing studies with animals Appropriate research study design is an important part of reducing the numbers of animals used in research and testing. We strongly recommend the free interactive course on designing animal experiments provided by Michael Festing. Designing and reporting animal experiments ANZCCART (NZ) endorses the PREPARE and ARRIVE guidelines for the designing and reporting of animal experiments involving the use of animals. The guidelines are intended to improve the planning and reporting of research using animals – maximising information published and minimising unnecessary studies. PREPARE guidelines for planning animal experiments can be found here . ARRIVE guidelines for reporting animal experiments can be found here . The ARRIVE reporting guidelines have been endorsed by over 1,000 scientific journals including nature, and the journals of the Royal Society Te Apārangi. A 3-minute video about the PREPARE guidelines can be found here . Animal welfare Please click to follow link for information on managing pain and anaesthesia in research animals. Alternatives to using animals in research, testing, or teaching Please click to follow link for information on alternatives to using animals in research, testing, or teaching. ComPass Animal Welfare Training This free online course covers the Australian Code and NZ Guide and welfare issues relating to animal use in research and teaching. Successful completion of Phase one of the course and its quiz fulfills the mandated basic training needs of researchers and teachers using animals as well as members of Animal Ethics Committees (AEC) in Australia and NZ (except AEC members in Victoria who are required to complete the Animal Welfare Victoria training). The aim is to standardize and augment the training offered for animal users in research and teaching throughout Australasia by offering this free online interactive and resource-rich course to all who need this training. For the course link and more information . Resource bank and recommendations on best practice There are ANZCCART resources and Links to r esources from other organisations that contain information and resources about animal welfare and alternatives to using animals. If you would like to add information or resources to this database please contact us . Information updates Our regular newsletter ANZCCART News contains updates on animal welfare, legislation and alternatives to using animals. If you are doing work that has animal ethics approval you should receive this newsletter (via email). If you have not been receiving a copy of ANZCCART News please contact us . Archived editions are available here . ANZCCART Conferences ANZCCART holds an annual conference which discusses animal welfare in the context of research, testing and teaching. The conference location varies and usually is held two successive years in Australia followed by one year in New Zealand. For more details please see our conference page . ANZCCART Contacts for questions If you have any questions or concerns please feel free to contact us .

ANZCCART Conference 2008 Blue Sky to deep water: the reality and the promise Proceedings of the 2008 ANZCCART Conference Auckland, New Zealand Preliminary pages Introduction Mark Fisher Welcome John Martin SESSION 1: Sharing experiences (dilemmas and compliance) Doing animal experimentation in a national organisation with regional responsibilities under state legislation Dr Chris Prideaux ( See PowerPoint presentation – PDF, 629 kb, 18 pages) Meeting animal welfare needs in a biotherapies environment- challenges for the CSL/Pfizer Animal Ethics Committee Dr John Phelps Assessing a research project with reference to the big picture Grant Shackell International benchmarking: AAALAC International Accreditation Dr Kathryn Bayne SESSION 2: Transgenics and modelling Modelling human muscle activity Professor Andrew Pullan Using zebrafish in human disease research: some advantages, disadvantages and ethical considerations Dr Michael Lardelli (See PowerPoint presentation – PDF, 5.6 MB, 26 pages) The benefits of using sheep to model human brain disease Jessie Jacobsen et al. SESSION 3: Great idea but not necessarily what I expected Great idea but not necessarily what I expected (Sometimes the techniques worked; sometimes they didn’t) Dr Allan Goldenthal, Dr Glen Harrison (See Powerpoint presentation – PDF, 1MB, 10 pages) Julie Hitchens ( PowerPoint presentation) Dr Jacqueline Keenan (PowerPoint presentation) Associate Professor Donald Love SESSION 4: Challenging ethics A brief but practical summary of ethics James Battye The Cam Reid Oration: Should we be giving attention to justifying animals in science? Dr Mark Fisher Infrared thermography and heart rate variability for non-invasive assessment of animal welfare Dr Mairi Stewart et al. (ANZCCART Student Award winner) ( PowerPoint presentation) SESSION 5: Death as an event, death as a challenge Euthanasing animals-the human experience Dr Erich von Dietz ( PowerPoint presentation) Managing grief associated with euthanasia Dr Dianne Gardner ( PowerPoint presentation) Recruiting Rats to the Research Resort: the importance of well trained resort personnel Dr John Schofield SESSION 6: Wildlife and conservation The artificial incubation of kiwi eggs: a conservation tool Suzanne Bassett and Claire Travers ( PowerPoint presentation) Researching wildlife in New Zealand: conservation opportunities are both constraints and opportunities Dr Mark Hauber Animal welfare issues in vertebrate pest management and research in New Zealand Dr Penny Fisher et al. SESSION 7: Fish welfare Working towards the development of best practices in fish and fisheries research or The troubles with fish and fish biologists! Howard Gill, Carolyn Ashton and Andrew Rowland The fish: What potential for awareness? Dr Colin Johnston ( PowerPoint presentation) “Pain” and analgesia in fish: What we know, what we don’t know, and what we need to know before using analgesics in fish Dr Don Stevens

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Openness Agreement The New Zealand Board of the Australian and New Zealand Council for the Care of Animals in Research and Teaching (ANZCCART), a Committee of the Royal Society Te Apārangi, has supported the development of an Openness Agreement on Animal Research and Teaching for New Zealand. A draft version of the Agreement went out for consultation in 2020/21, and was launched at the ANZCCART 2021 conference on 27 July 2021: Press release about launch of Openness Agreement Media coverage: New Zealand Herald ; Science Media Centre NZ ; Radio New Zealand ; Farmers Weekly; the Mandarin New Zealand has long been committed to maintaining and improving high standards of animal welfare as well as undertaking world-leading research and teaching using animals. Those involved in research have an obligation to demonstrate and promote these values, and in order to be seen as trustworthy they must be open, transparent, and accountable for the research and teaching that they conduct, fund or support, including when the high standards they strive for are not achieved. Doing more to communicate the context in which animal research and teaching takes place, the work that organisations undertake to incorporate the Three Rs (the Replacement, Refinement and Reduction of animals), the regulations that govern this research, and the systems that are in place to report and rectify poor practice is key. The objective of this Agreement is to ensure that the public are well informed about what animal research involves, the role it plays in the overall process of scientific discovery, how such research is regulated in New Zealand, and what researchers and animal care staff do to promote welfare, reduce animal usage and minimise suffering and harm to the animals. Several countries have now implemented (or are actively working on) formal ‘openness agreements’ to improve public understanding of animal research. Under such agreements, stakeholders make a public pledge to be more open about their involvement in animal research and explain details and reasons underlying it. The European Animal Research Association has several examples of openness agr eements. The longest established openness agreement is the UK Concordat on Openness on Animal Research . The UK Concordat has operated successfully since 2014 and now has over 120 signatories representing leading universities, research institutes, government agencies, funders and industry. Commit m e nts The Openness Agreement on Animal Research and Teaching in New Zealand sets out five Commitments that require signatories to take steps to be more open about the use of animals in research and teaching. The five commitments are: We will be clear about why and how we use animals in research and teachin g. We will enhance our communications with the media and the public about our use of animals in research and teaching. We will be proactive in providing opportunities for the public to find out about research and teaching using animals. We will enhance our communications with tangata whenua about our use of animals in research and teaching. We will report on progress annually and share our experiences. Following a review of the Agreement in 2024, an additional category of "Supporter" was added as a type of signatory for organisations that do not conduct animal research or teaching directly but have indirect involvement in ways such as providing funding, regulatory oversight, supplying equipment or animals for, or serving as professional bodies. View the agreement here: ANZCCART Openness Agreement on Animal Research and Teaching in New Zealand – 2025 Openness Agreement Annual Report Signatories report annually on their progress and share experiences: 2022 An nual Report: Download (Press Release ) (infographic ) 2023 Annual Report: Download (Press Re lease ) (infographic ) 2024 Annual Report: Download (Press Release ) (infographic ) 2025 Annual Report: Download (Press Release ) (infographic ) Signatories The signatories to this agreement are: Research & Teaching Signatories Supporter Signatories If your organisation would like to join the Agreement, please contact: anzccart@royalsociety.org.nz

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