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Animal welfare What is animal welfare and whose welfare is considered? Animals are recognized as sentient beings in New Zealand law. This means they have sufficiently complex nervous systems to support flexible and adaptive behaviour and, importantly, a range of different experiences and feelings that they can interpret as good/positive or bad/negative. In New Zealand, animals considered to be sentient are mammals, birds, reptiles, amphibians, fish, octopus, squid, crabs, lobsters and crayfish (see Information about animal research in NZ for more information). The welfare of an animal depends on its mental state – the negative or positive experiences it is having at a particular point in time. Negative experiences might include pain, discomfort, breathlessness, nausea, fear, anxiety, hunger, thirst and even loneliness, frustration or boredom, depending on the kind of animal. Good experiences might include feelings of pleasure, comfort, safety and companionship, again depending on the kind of animal. The animal’s mental state is influenced by its perception of both its physical health and its environment. How can we understand an animal’s welfare state to make improvements? Often in research, it is necessary to perform procedures that may cause animals to experience negative states like fear, pain, nausea, or breathlessness. In addition to compromise during procedures, animals may also experience compromise in their home environment, during day-to-day husbandry and handling, preparation for, as well as recovery from, the procedure. An animal may be more likely to experience welfare compromise because of its age, physical state, particular type or breeding. When using animals in research, testing, and teaching, we have a responsibility to promote good welfare, meaning minimizing welfare compromise due to negative experiences and enhancing welfare by providing opportunities for positive experiences. The people responsible must consider the ways that their use of, or interaction with, the animals may impact their welfare. Another way to think about this is to ask “What mental states will the animal experience in this situation, in this physical condition or due to this procedure?”. We can understand the degree to which welfare is compromised by evaluating the quality, likelihood, severity/intensity and duration of any and all negative experiences; we do this using observable or measurable indicators of mental states, including behavioural, physiological and neurophysiological measurements. Likewise, we can understand the degree of welfare enhancement, primarily by evaluating animal’s behavioural responses to opportunities that arise or we provide. One model we can use to organize investigations of welfare and the evidence for an animal’s mental experiences and its overall welfare state is the Five Domains Model. This is an internationally recognised welfare assessment framework developed in New Zealand. It reflects modern understanding of animal welfare by breaking down the factors that influence welfare into four categories (Domain 1 Food and water; Domain 2 Physical environment; Domain 3 Health and physical status; Domain 4 Behavioural interactions) and includes the associated mental experiences in a fifth category (Domain 5 Mental states). With care, the Model can be used for any species in any context. It allows the user to apply their own knowledge of the animal species to identify potential sources of welfare compromise and opportunities for welfare enhancement. How can we improve the welfare of animals used in RTT? The Three Rs The Three Rs provide guidance on ways to minimize welfare compromise for animals used in RTT by avoiding animal use altogether (Replacement), reducing the number of animals that might experience welfare compromise whilst still achieving the purpose of having used them (Reduction) or reducing the likelihood, severity and/or duration of negative mental experiences arising due to the ways animals are used and managed (Refinement). Providing opportunities for positive experiences, while continuing to minimise negatives, is another way to refine animal use. For more information about the Three Rs see NC3Rs . Minimizing welfare compromise (Refinement) depends on what the problem is for the animal. Importantly, animals must be conscious to be having any mental experiences, including pain, so using general anaesthesia to make an animal unconscious is one way to reduce welfare compromise during a procedure. Pain can also be alleviated or reduced by using drugs that block or reduce pain signals (local anaesthetics or analgesics). However, pain-relieving drugs won’t reduce hunger, thirst, breathlessness, nausea, fear or loneliness. So, the remedy must be appropriate for the problem, and the effectiveness of the intervention should be evaluated using methods like those described above. For example, fear due to human-animal interactions can be reduced by avoiding or refining handling procedures, while anxiety might be relieved by manipulating animal housing or social groupings. Likewise, such changes in animal housing and management can provide animals opportunities for positive experiences. Promoting these feelings wherever possible can enhance the welfare of animals, as well as making them easier to handle and work with. Resources for minimizing welfare compromise: Beausoleil, N., & Mellor, D. (2015). Introducing breathlessness as a significant animal welfare issue. New Zealand Veterinary Journal , 63 (1), 44–51. https://doi.org/10.1080/00480169.2014.940410 Resources for enhancing welfare: ·Baumans, V. (2005). Environmental Enrichment for Laboratory Rodents and Rabbits: Requirements of Rodents, Rabbits, and Research. ILAR Journal , 46 (2), 162–170. https://doi.org/10.1093/ilar.46.2.162 Rault, J.-L., Waiblinger, S., Boivin, X., & Hemsworth, P. (2020). The Power of a Positive Human–Animal Relationship for Animal Welfare. Frontiers in Veterinary Science , 7 . https://www.frontiersin.org/articles/10.3389/fvets.2020.590867 Resources for understanding animal welfare and its assessment: Mellor, D. J. (2017). Operational Details of the Five Domains Model and Its Key Applications to the Assessment and Management of Animal Welfare. Animals, 7(8), Article 8. https://doi.org/10.3390/ani7080060 Mellor, D. J., Beausoleil, N. J., Littlewood, K. E., McLean, A. N., McGreevy, P. D., Jones, B., & Wilkins, C. (2020). The 2020 Five Domains Model: Including Human–Animal Interactions in Assessments of Animal Welfare. Animals, 10(10), 1870. https://doi.org/10.3390/ani10101870 Littlewood, K.E.; Beausoleil, N.J.; Mellor, D.J. Updating the Five Provisions: Aligning Welfare-Focused Care with the Five Domains Model. Animals 2026 , 16 , 1927. https://doi.org/10.3390/ani16121927

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Media Information This page provides information on recent press releases, an image database, and web resources related to the use of animals in research, testing or teaching. Press releases 6 July 2026: 274,985 animals used in research, testing and teaching in New Zealand in 2025, according to new government figures 10 March 2026: Transparency, public access, and Māori partnership surge across animal research in Aotearoa— ANZCCART report 21 January 2026: ANZCCART NZ responds to Ministry for Primary Industries’ release of 2024 statistics on the use of animals in research, testing and teaching 20 March 2025: ANZCCART NZ releases third annual report on Openness Agreement for animal research and teaching 20 March 2025: ANZCCART NZ responds to New Zealand's animal research statistics for 2023 10th September 2024: New animal ethics resources include Māori knowledge 17 May 2024: A good step-up in Three Rs reporting and other positive trends: 2022 New Zealand Animal Research, Testing and Teaching Statistics 8 March 2024: ANZCCART New Zealand releases second annual report on Openness Agreement for animal research and teaching 13 November 2023: New Study Reveals New Zealanders' Views on Animal Use in Scientific Research and Teaching 21 August 2023: A step forward in openness in animal research and teaching but more progress needed in Three Rs reporting: New Zealand's Animal Research Statistics of 2021 30 March 2023: ANZCCART releases first report on Openness Agreement in Animal Research and Teaching 30 May 2022: Openness on use of animals in research testing and teaching statistics 27 July 2021: Science organisations pledge openness in animal research and teaching in New Zealand 1 September 2017: New resources highlight innovative ways to replace, reduce and refine the use of animals in research Submissions 21 May 2024: Submission to the Science System Advisory Group - First Phase Media coverage 04 February 2026: Decline in high impact on animals from research 'encouraging ' 24 September 2024: Maori knowledge of animals 21 March 2024: Global initiative to make animal research more transparent turns 10 – has it worked? 13 November 2023: Attitudes towards animal testing and research in Aotearoa – Expert Reaction Image database for the use of animals in research, testing or teaching An image database featuring copyright free images of animals suitable for use in stories on animal use in testing, teaching and research is available through the Understanding Animal Use website (UK based). This website also contains a number of resources on the use of animals in research.

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