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Openness Agreement The New Zealand Board of the Australian and New Zealand Council for the Care of Animals in Research and Teaching (ANZCCART), a Committee of the Royal Society Te Apārangi, has supported the development of an Openness Agreement on Animal Research and Teaching for New Zealand. A draft version of the Agreement went out for consultation in 2020/21, and was launched at the ANZCCART 2021 conference on 27 July 2021: Press release about launch of Openness Agreement Media coverage: New Zealand Herald ; Science Media Centre NZ ; Radio New Zealand ; Farmers Weekly New Zealand has long been committed to maintaining and improving high standards of animal welfare as well as undertaking world-leading research and teaching using animals. Those involved in research have an obligation to demonstrate and promote these values, and in order to be seen as trustworthy they must be open, transparent, and accountable for the research and teaching that they conduct, fund or support, including when the high standards they strive for are not achieved. Doing more to communicate the context in which animal research and teaching takes place, the work that organisations undertake to incorporate the Three Rs (the Replacement, Refinement and Reduction of animals), the regulations that govern this research, and the systems that are in place to report and rectify poor practice is key. ​ The objective of this Agreement is to ensure that the public are well informed about what animal research involves, the role it plays in the overall process of scientific discovery, how such research is regulated in New Zealand, and what researchers and animal care staff do to promote welfare, reduce animal usage and minimise suffering and harm to the animals. Several countries have now implemented (or are actively working on) formal ‘openness agreements’ to improve public understanding of animal research. Under such agreements, stakeholders make a public pledge to be more open about their involvement in animal research and explain details and reasons underlying it. The European Animal Research Association has several examples of openness agr eements. The longest established openness agreement is the UK Concordat on Openness on Animal Research . The UK Concordat has operated successfully since 2014 and now has over 120 signatories representing leading universities, research institutes, government agencies, funders and industry. Commit m e nts The Openness Agreement on Animal Research and Teaching in New Zealand sets out five Commitments that require signatories to take steps to be more open about the use of animals in research and teaching. The five commitments are: We will be clear about why and how we use animals in research and teachin g. We will enhance our communications with the media and the public about our use of animals in research and teaching. We will enhance our communications with tangata whenua about our use of animals in research and teaching. We will be proactive in providing opportunities for the public to find out about research and teaching using animals. We will report on progress annually and share our experiences. ​ View the agreement here: ANZCCART Openness Agreement on Animal Research and Teaching in New Zealand – September 2023 ​ Openness Agree m ent Annual Report Signatories report annually on their progress and share experiences: ​ 2022 An nual Report: Download (Press Release ) (infographic ) ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ Signatories The signatories to this agreement are: If your organisation would like to join the Agreement, please contact: anzccart@royalsociety.org.nz

2024 ANZCCART Conference If you would like to know more on the latest developments on animal welfare and meet people that have a passion for working with animals, this is an opportunity for you. ANZCCART hosts conferences annually where you get to hear great presentations, participate in workshops, hear different view points on the ethics of use of animals, and build networks with those interested in the many aspects of animal care. For more information on the upcoming conference or if you would like to view Proceedings of previous conferences please see below The 2024 ANZCCART Conference will be held in Christchurch from 10-12 September, with a theme around the use of animals in education and training. Archive of ANZCCART Conference proceedings: 2022 ANZCCART Conference - Melbourne 26-28 July (PDF 3.4MB, 99 pages) 2021 ANZCCART Conference – Openness in Animal Research (PDF 7.2MB, 160 pages) Exploring the benefits and risks of openness in regards to the use of animals in Australian and New Zealand research. View the conference proceedings View the conference presentations The 2021 conference (delayed from 2020) looked at ‘openness’ in animal research and teaching. Public confidence in animal research hinges on the scientific community engaging in the evolving conversation about how and why animals are used. Being open about these matters is a worthwhile endeavour, and to be encouraged. To gain a broader perspective on how openness looks in practise, the conference examined overseas examples, both success stories and failures, and learn from different cultural viewpoints. 2019 ANZCCART Conference – Breaking Down Laboratory Walls (PDF 4.1MB, 138 pages) 2018 ANZCCART Conference – Keeping it Relevant (PDF, 198 pages) 2017 ANZCCART Conference – Maintaining social license in a changing world (PDF) Part 1 , Part 2 The theme of the conference was maintaining social licence in a changing world. The conference covered a wide range of topics from addressing social license in different contexts, to advances in replacement, reduction and refinement technologies, lessons from animal ethics committee front lines, and animal handling. 2016 ANZCCART Conference – Man or Mouse (PDF, 3.5 MB, 109 pages) 2015 ANZCCART Conference – Animal ethics – the gold standard 2014 ANZCCART Conference – Mixing it up – ethics, science, and adventure tourism (PDF 1.7MB, 106 pages) The use of animals for research and teaching can be awkward. Necessary, justifiable, ethical, well managed, well regulated without doubt. But still it can be awkward. It raises awkward questions. The conference sought to provide good answers to those questions. 2013 ANZCCART Conference – Can we do better? (PDF, 3.96 MB, 162 pages) 2012 ANZCCART Conference – Thinking Outside the Cage: A different point of view (PDF, 2 MB, 128 pages) 2011 ANZCCART Conference – Science with feeling: animals and people (ANZCCART website) The eclectic mix of contributions in these proceedings recognise the complex interdependence between animals and people, an inextricable connection woven with feelings. 2010 ANNZART Conference – Ethics in a changing environment (PDF) 2009 ANZCCART Conference – AEC best practice (PDF, 3.2 MB, 126 pages) 2008 ANZCCART Conference – Blue Sky to deep water: the reality and the promise (ANZCCART website) The contributions to the 2008 conference "Blue sky to deep water: the reality and the promise" held in Auckland, New Zealand, reflect the conference presentations dealing with science, values and the reality of understanding “backward running rats” and “cunning fighting fish”. 2007 ANZCCART Conference – Getting it Right (PDF, 1 MB, 120 pages) 2006 ANZCCART Conference – Responsibilities – The 4th R (PDF, 2.9 MB, 175 pages) 2005 ANZCCART Conference – Animal Ethics Committees and animal use in a monitored environment: is the ethics real, imagined or necessary? (PDF, 2.6 MB, 98 pages) The conference focused on what Animal Ethics Committees do in regulating and monitoring the use of animals in research and teaching, and the public’s and scientists’ expectations of the process. 2004 ANZCCART Conference – Animal Ethics: New Frontiers, New Opportunities (PDF, 1 MB, 44 pages) 2003 ANZCCART Conference - Lifting the veil: finding common ground 2003 - ANZCCART .pdf Download PDF • 12.55MB The theme of this ANZCCART Conference is "Lifting the veil: finding common ground". This theme was borne out of a perceived need to respond in a positive way to concerns that have been expressed in New Zealand regarding secrecy in the regulatory processes governing animal research. 2003 ANZCCART Workshop - Monitoring Animal Welfare and Promoting Refinement (PDF) 2002 ANZCCART Conference – Animal welfare and Ethics Committees. Where are the goalposts now? (PDF, 2.2 MB, 94 pages) 2001 ANZCCART Conference – Learning, animals and the environment: Changing the face of the future (ANZCCART website) 2001 ANZCCART .pdf Download PDF • 8.97MB Exploring the relationships between ourselves, animals, and the environment was the theme of the conference jointly organised by ANZCCART and the National Animal Ethics Advisory Committee (NAEAC). Issues to be addressed included the interdependence and interconnectedness of all life, the images of science and scientists, relevant legislation, dealing with new technology, fish research, and what could and should statistics or the popular media tell us. 1999 AWAC/ANZCCART Conference - Innovation, ethics, and animal welfare: public confidence in science and agriculture 1999_ANZCCART .pdf Download PDF • 11.50MB The conference placed the welfare of animals squarely in the context of the challenges posed by changing patterns ofinternational trade, scientific and technological innovation, and societal attitudes. A central issue was that of the relationship between the wider community-including producers and consumers of livestock products-and scientists. 1997 ANZCCART/NAEAC Conference - Ethical approaches to animal-based sceince 1997_ANZCCART .pdf Download PDF • 16.20MB Ethical approaches to animal-based science emphasises value systems. Value systems are of importance to all of those concerned with animalbased science, whether as proponents or opponents of it. 1995 ANZCCART Conference - Farm animals in Biomedical and Agricultural Research 1995_ANZCCART .pdf Download PDF • 8.98MB This was the sixth conference held by ANZCCART and the second in New Zealand. Its theme moved from the narrower area of traditional laboratory animals to encompass the much wider field of farm animals in biomedical and agricultural research. 1994 ANZCCART Conference - Animal welfare in the twenty-first century: ethical, educational and scientific challenges 1994_ANZCCART .pdf Download PDF • 10.91MB The conference considered what directions animal welfare thinking might take in the future, the implications of those directions for human uses of animals in education and science, and the initiatives we would like to see taken to safeguard the welfare of the animals used in the educational and scientific arenas.

About Us ANZCCART is an independent body which was established to provide leadership in considering ethical, social and scientific issues relating to the use and wellbeing of animals in research and teaching; and to provide a focus for information and advice concerning the ethical and scientific use of animals in research and teaching . In New Zealand, ANZCCART comprises representatives from the research, animal welfare and education communities, and is a standing committee of the Royal Society Te Apārangi. “The Committee meets regularly during the year to advance our underlying purpose to promote discussion around the social, ethical and scientific use of animals in research and teaching. We believe we contribute to a social license for such use by promoting the highest standards of care and consideration. Central to our philosophy is the active deployment of the “Three R’s” – the refinement, reduction and replacement of animals in research and teaching. Such discussions can be challenging. We facilitate them because we believe in considered and informed debate.” Hon Pete Hodgson, Chair – ANZCCART (NZ) (2012-2020) Our Mission Our corporate mission is to promote: Excellence in the care of animals supplied for or used in research, testing (within New Zealand), and teaching; Responsible scientific use of animals; The Three Rs: Replacement, Reduction and Refinement as they apply to the use of animals for scientific purposes; Informed discussion and debate within the community regarding these matters; Strategic partnerships to contribute to the education and training of scientists, students and the broader community. ANZCCART operates on a purely advisory basis and provides guidance and information to all interested parties including Animal Ethics Committees (AEC), scientists, teachers, regulatory authorities, granting agencies, government, animal welfare organisations, the media and the general public. ANZCCART NZ Board Terms of Reference 2022 .pdf Download PDF • 234KB Our People New Zealand Board Members: Emeritus Professor Pat Cragg (Chair), retired, formerly University of Otago (2022-2024) Chair of the ANZCCART New Zealand Board since April 2020. Pat is a physiologist, and from undergraduate training, a zoologist; her research area covered cardiorespiratory function and control in health and disease; her breadth of teaching is typified as a co-editor of a long-standing physiology textbook. Prior to retirement in May 2018, she held appointments at the University of Otago, for instance as Head of Department of Physiology, Associate Dean Academic Health Sciences and Acting Dean of School of Biomedical Sciences. Pat was on the University's Animal Ethics Committee for 27 years and on the ANZCCART New Zealand Board for 18 years, with four years as Deputy Chair, as well as seven years as the NZ representative on the ANZCCART Australian Board. For many years Pat was Secretary of the Physiological Society of NZ and Chair of the Scientific Committee of the Otago Medical Research Foundation (OMRF). she now Chairs the OMRF Council. From mid-April 2019 to the end of January 2022, she returned from retirement to be the Acting Deputy Vice-Chancellor Academic at the University of Otago. Dr Arnja Dale (Deputy Chair), Chief Scientific Officer, Royal New Zealand SPCA (2022-2024) Arnja has over 20 years working in the field of animal welfare science in New Zealand and overseas. Arnja is the Chief Scientific Officer at SPCA New Zealand. Prior to joining SPCA, Arnja was a Senior Lecturer in Animal Welfare Science, Ethics and Law, leading numerous research projects, and also led the animal welfare investigations training programme at Unitec. She is a current member of the ANZCCART NZ, the National Animal Welfare Advisory Committee (NAWAC) and the National Animal Ethics Advisory Committee (NAEAC). Arnja is passionate about animal welfare science and changing the hearts and minds of the next generation through evidence-based education initiatives. Arnja lives in Auckland with her husband, 3 children, and her dog and cat. Professor Ngaio Beausoleil, School of Veterinary Science, Massey University (2023) Ngaio is Professor of Animal Welfare Science and Co-Director of the Animal Welfare Science and Bioethics Centre, School of Veterinary Science, Massey University, NZ. She has been active in research, teaching and scholarship in relevant areas of animal physiology, behaviour and welfare science for 20 years. Her research employs behavioural and physiological methods to investigate various aspects of animal welfare in both domestic and wild animal species. A key strength is her systematic, science-based approach to evaluating animal welfare impacts and she has been closely involved in the evolution of the Five Domains Model for more than a decade. Ngaio provides scientific support, advice and research to governments, various animal industries and veterinary professional bodies in New Zealand and around the world. As well as being a member of ANZCCART, she is Chair of the New Zealand Veterinary Journal editorial board, an independent scientific expert on the Wellington Zoo Animal Welfare Committee and Massey liaison to the UK Universities Federation for Animal Welfare. She gets a real buzz out of working with postgraduate research students. Life outside of work includes children, horses and downhill mountain biking. Dr Sally Birdsall, Senior Lecturer, Faculty of Education, University of Auckland (2022-2024) I’m Sally Birdsall and I work at the Faculty of Education and Social Work in the University of Auckland. I teach and research in science and sustainability education with a focus on pedagogy – the theories, approaches and strategies that can be used to teach and learn effectively. In my work with ANZCCART New Zealand, I have led the development of two resources for secondary students where they can learn about the way scientists work with animals to produce scientific knowledge and think critically about the interconnectedness of science and society. Outside of work, I spend time with my three granddaughters and working to restore the biodiversity of the native bush remnants at my place and the reserve next door. I’m starting to see the effects of the restoration - the tūī population is growing each year and I’ve been visited by two kākā, native birds that have not been seen in my area for over 30 years. Vanessa Borman, Animal Ethics Coordinator, AgResearch (2023-2025) I have an MSc in Toxicology and experience in laboratory animal research, science administration and animal ethics. My inspiration is a love of science, animals and working with people. My current role is AgResearch Animal Ethics Coordinator which has provided the opportunity to travel and meet interesting people doing amazing things. I bring energy and action with a unique perspective on science and ethics. Associate Professor Justin Dean, Department of Physiology, University of Auckland (2021-2023) I study brain development, how it can be affected by premature birth, and ways to try to prevent or restore deficits in brain development. I was always fascinated by science, particularly the brain. I love the intellectual freedom associated with running a research laboratory and the training and teaching of younger scientists. After my PhD, my wife and I lived in Sweden and the USA as part of my postdoctoral training, and had children in those countries. Another highlight was the opportunity to return to NZ with family to start faculty research and teaching position at the University of Auckland. I am involved in coaching kids sports (cricket, netball, rugby), and also enjoy surfing, running, and cooking. Dr Mike King, Senior Lecturer, Bioethics Centre, University of Otago (2022-2024) I’m Head of Department at the Te Pokapū Matatika Koiora the Bioethics Centre, within the Dunedin School of Medicine and the Division of Health Sciences at the University of Otago. Bioethics Centre staff and students research, teach and learn about of the rights and wrongs (that is to say, the ethics) of healthcare and the biosciences. A lot of my work focuses on the ethics of animal use in research. I used to do animal research, which was the beginning of my path to my present career in bioethics. I come from the small town of Te Puke in the North Island of New Zealand. It has a sign saying it’s the kiwifruit capital of the world and has an enormous slice of kiwifruit on display to back it up. Dr Kate Littin, Associate Member representative (2022-2024) Kate Littin has worked at the Ministry for Primary Industries where she got to satisfy her deep interest in applying science to animal welfare policy. Kate’s farm upbringing and early interest in stress and animal behaviour led her to complete a PhD on the impacts of pesticides on possums and rats. This experience with humane pest control serves her well now as she and her family restore a beautiful wetland. Mr Tipene Merritt, Kaiārahi Rangahau Māori, University of Canterbury (2023-2025) I am the key advisor of Ko Aotearoa Tēnei (Wai 262) - Māori interests in research concerning native flora and fauna; have Governance role of an Australian Co-operative Research Centre, Future Farm Industries; and develop mutually beneficial research relationships between Māori communities and Universities. I am looking to add a Māori viewpoint and a research management perspective to the social, ethical and scientific use of animals in research and teaching. I am completing a PhD on the interface between Mātauranga Māori and the Intellectual Property Rights system. Further to this I am an active member in hapū/iwi affairs and I also practice yoga. Ian Saldanha, Biosecurity Compliance Coordinator, Cawthron Institute (2023-2025) I have been involved in the lab animal industry for over 10 years. Before taking up a position at the Cawthron Institute in Nelson, I was the Head of the Animal facility at the Malaghan Institute in Wellington. This is where my passion for working with animals grew. During this time, I served on the executive committee for Australia New Zealand Laboratory Animal Association (ANZLAA) for a few years where I used this opportunity to support those that work in the animal science field and meet others from the industry. One of the highlights in my career was getting the opportunity to travel the world, visit other animal facilities, and gain an understanding about how they operate. Outside my profession I have a love for the outdoors in particular running. I enjoy travelling, meeting new people, and of course spending time with my family. ANZCCART Fellow (observer) Ms Morgan Heslop, PhD student, Animal Welfare Science and Bioethics Centre, Massey University (2023-2025) My research expertise is in animal welfare science, and I am particularly interested in how we understand the inner lives of animals. I was inspired to pursue a career in research when I learned of an entire scientific discipline dedicated to answering questions I had been asking myself for years! What I love most is discussing welfare and ethics with people who share my enthusiasm – or who can be convinced to! Our members (funders): Along with Unitec|Te Pūkenga. If you are interested in becoming a member, please contact ANZCCART (NZ). Background to ANZCCART (NZ) ANZCCART is governed by separate Boards in New Zealand and Australia. ANZCCART (NZ) is a committee of the Royal Society Te Apārangi. Its principal sponsors are Universities New Zealand and AgResearch Ltd but it also receives annual contributions and/ or other support from organisations including the Ministry for Primary Industries and the Royal New Zealand SPCA. ANZCCART (NZ) promotes and supports the commitment to the principles embodied in the New Zealand legislation regulating the use of animals in research, testing and teaching in New Zealand ( Animal Welfare Act 1999, Part 6 ). Further information is available on the animal welfare principles of the Three Rs and ANZCCART’s History. History of ANZCCART ANZCCART, the Australian and New Zealand Council for the Care of Animals in Research and Teaching, was established on the 1st of January, 1993, as a result of a collaborative effort between the Australian Council for the Care of Animals in Research and Teaching (ACCART, established in May 1987) and various New Zealand authorities, including the Ministry of Agriculture and Fisheries (now known as the Ministry for Primary Industries) and the Royal Society of New Zealand (now Royal Society Te Apārangi). In New Zealand, this followed decades of efforts by the Society to promote and progress the humane use of animals in science. The Australia-New Zealand collaboration aimed to address the growing need for ethical and scientific guidance in the use of animals for research and teaching purposes in both countries. In New Zealand, ANZCCART operates as a committee of the Royal Society Te Apārangi, maintaining strong connections with its Australian counterpart. New Zealand formed a standing committee of the Royal Society and joined ACCART to form ANZCCART in 1993. The joint name was to emphasise united efforts in promoting the ethical use of animals in research and teaching across both nations.This partnership has allowed the organizations to share resources, expertise, and knowledge while working towards common goals. For a comprehensive understanding of ANZCCART's history, we recommend reading the article “ Reflections on the use of animals in research, testing and teaching in New Zealand – a historical perspective. ” by Dr David Bayvel et al. (2011). (PDF, 653 kb, 4 pages) This article offers valuable insights into the development of ANZCCART and the progress made over the years in improving the ethical and scientific use of animals in research, testing, and teaching in both Australia and New Zealand. Resource links about ANZCCART and animal welfare in New Zealand The following resources about ANZCCART and animal welfare in New Zealand are available: Animal Research Saves Lives (ANZCCART resource) (PDF, 1.8 MB, 14 pages) Animal welfare in NZ (Ministry of Primary Industries) ANZCCART Annual Report (PDF, 1.5 MB, 46 pages) ANZCCART Newsletters Culture of Care (NAEAC guide for people working with animals in research, testing and teaching) (PDF) SPCA New Zealand The National Animal Ethics Advisory Committee (NAEAC) website The National Animal Welfare Advisory Committee (NAWAC) website What is ANZCCART (2017)(ANZCCART resource) (PDF, 428 kb, 1 page)

Information on animal ethics and legislation in New Zealand It is the responsibility of everyone who uses animals to ensure that they are only used when absolutely necessary and that when they are used they are treated with care and respect. If an animal is used for research, testing or teaching the work must be conducted in line with the Three Rs (from the ideas of Russell and Burch in their 1959 book The principles of humane experimental technique available through the Johns Hopkins Alt Web website). Replacement Where possible an alternative to using animals must be used. This could include a computer model or cell culture (where animal or human cells are grown in a laboratory). Reduction The minimum number of animals must be used to gain good experimental results. This means that experiments must be well designed and that as many experimental variables as possible are controlled (i.e., that you only change one thing in your experimental group as compared to your control group). This means that the research or test will provide quality data which can withstand statistical analysis. Refinement The animals should not suffer. At all times the health and wellbeing of animals should be a priority. As much as possible the animal should be able to live normally, free from any pain and suffering, throughout the research, teaching or testing process. To gain ethical approval to work with animals (research, testing or teaching) you must submit an application to an Animal Ethics Committee (AEC). Most research institutions (e.g. university) have their own Animal Ethics Committees. To find out how to apply you should contact your Head of Department or the research office of your institution. If you work in an institution or company that does not have an Animal Ethics Committee please contact the Ministry for Primary Industries ( animalwelfare@mpi.govt.nz ) for advice on how to proceed. Legislation on the use of animals in research, testing and teaching In New Zealand the use of animals in research, testing and teaching is controlled by the Animal Welfare Act 1999 . This legislation is designed to protect animals in NZ from harmful or inhumane treatment. It covers our obligation to care for animals; who can conduct surgical procedures on animals; animal exports; humane treatment of wild animals; and codes of welfare. For information on the control of animal use in research, testing and teaching under the Animal Welfare Act 1999, see the Ministry for Primary Industries website . Anyone wishing to carry out any form of research, testing or teaching on an animal must first apply for approval from an Animal Ethics Committee. Approval is normally sought by a lead investigator or teaching team leader. Once approval is given it will allow the named students and employees to carry out the animal work provided they are adequately trained and are fully aware of the protocols, including those around animal care.

Information for New Zealand Media This page provides information on recent press releases, an image database, and web resources related to the use of animals in research, testing or teaching. Press releases 21 August 2023: A step forward in openness in animal research and teaching but more progress needed in Three Rs reporting: New Zealand's Animal Research Statistics of 2021 30 March 2023: ANZCCART releases first report on Openness Agreement in Animal Research and Teaching 30 May 2022: Openness on use of animals in research testing and teaching statistics 27 July 2021: Science organisations pledge openness in animal research and teaching in New Zealand 1 September 2017: New resources highlight innovative ways to replace, reduce and refine the use of animals in research Image database for the use of animals in research, testing or teaching An image database featuring copyright free images of animals suitable for use in stories on animal use in testing, teaching and research is available through the Understanding Animal Use website (UK based). This website also contains a number of resources on the use of animals in research. Resources Understanding Animal Research (UK website) Animal Welfare Act 1999 (Parliamentary Council Office website) Guide to the Animal Welfare Act (Ministry for Primary Industries website) The National Animal Ethics Advisory Committee (NAEAC) website The National Animal Welfare Committee (NAWAC) website SPCA New Zealand Alt web (resource database hosted by Johns Hopkins University) Annual Report (PDF, 1.5 MB, 46 pages)

ANZCCART Conference 2011 Science with feeling: animals and people Proceedings of the 2011 ANZCCART Conference Rotorua, New Zealand Contents and Foreword Opening Address Reflections on the use of animals in research, testing and teaching in New Zealand – a historical perspective – Dr A. C. David Bayvel, Linda Carsons, Paula Lemow and Dr Mark Fisher International reflections: looking back over the last 20 years – Dr Judy A. MacArthur Clark Session 1: I don’t like pain but what can we do about it? What’s special about pain? – Dr John Schofield “I’ll have the fish and shrimps”: pain and analgesia in invertebrates and fish – Dr Kurt K. Sladky The recognition and relief of pain in birds – Associate Professor Brett Gartrell Analgesia in ruminants – Dr Paul Chambers Cam Reid Oration 2011: Does the fetus feel pain, and why do we care to know? Professor Laura Bennet Session 2: Resolving the dilemmas Serving on an Animal Ethics Committee – a hospital pass or a valued distinction? Dr Mark Oliver Dr Geoff Dandie Serving on an Animal Ethics Committee – the system and pot pourri of issues Who qualifies as an investigator? – Dr Erich von Dietze and Dr Ted Rohr Animal Ethics Committees: a veterinary practitioner’s point of view – Dr Tim Mather Animal welfare in a new world – Jeanette Crosado Reflections on an Animal Ethics Committee – Dr Mandy Paterson ANZCCART New Zealand Animal Care Technicians’ Awards Compassion fatigue – Debbie Chesterfield Welfare in a chronic model of cardiac disease in sheep – Linley Nisbet Session 3: The importance of people Euthanasia in the workplace – impacts on staff – Professor Peter Davie Caring for the carers: compassion fatigue and disenfranchised grief – Dr Peter Huggard Reviewing the reviews: an update on the analysis of the process of ensuring regulatory compliance in the use of animals in science in New Zealand – Dr Virginia Williams and Linda Carsons Seeking nature in the city: the implications of feeding wildlife – Associate Professor Darryl Jones Female students’ attitudes towards the use of animals in scientific research and teaching – Sally Birdsall and Dr Beverley France Student and university perspectives on animal rights and wrongs – Dr Ngaio J. Beausoleil Animal models: their role in understanding brain dysfunction – Dr Ruth M. A. Napper Session 4: Science with feeling Science with feeling: relevance of animal emotions to research, testing and teaching – Dr Jim Webster Methodologies to measure affective states in animals: a focus on cognitive approaches – Dr Else Verbeek and Dr Caroline Lee What is it like to be a rat? Providing good environments for experimental animals – Dr Emily Patterson-Kane and Professor David J. Mellor

Animal welfare Information on how to better manage pain in research animals The following articles have been selected by panel members of ANZCCART to help researchers and AEC members improve their understanding of anaesthesia in research animals. Resources on how to improve anaesthesia in research animals Richebé, Philippe, et al. “Ketamine improves the management of exaggerated postoperative pain observed in perioperative fentanyl-treated rats.” Anesthesiology 102.2 (2005): 421-428. (Read the Richebe Abstract ) Langford, Dale J., et al. “Coding of facial expressions of pain in the laboratory mouse.” Nature methods 7.6 (2010): 447-449. (Read the Langford Abstract ) Information on anaesthesia in research animals The following articles have been selected by panel members of ANZCCART to help researchers and AEC members improve their understanding of anaesthesia in research animals. For a selection of resources we recommend publications by Paul Flecknell such as Anaethesia in research animals . Resource links on anaesthesia in research animals Saha, Joy K., et al. “Acute hyperglycemia induced by ketamine/xylazine anesthesia in rats: mechanisms and implications for preclinical models.” Experimental Biology and Medicine 230.10 (2005): 777-784. (Read the Saha Abstract ) Eintrei, Christina, L. Sokoloff, and C. B. Smith. “Effects of diazepam and ketamine administered individually or in combination on regional rates of glucose utilization in rat brain.” British journal of anaesthesia 82.4 (1999): 596-602. (Read the Eintrei Abstract ) Curtin, Leslie I., et al. “Evaluation of buprenorphine in a postoperative pain model in rats.” Comparative medicine 59.1 (2009): 60. (Read the Curtin Abstract ) Toth, Linda A. “Defining the moribund condition as an experimental endpoint for animal research.” ILAR Journal 41.2 (2000): 72-79. (Read the Toth Abstract )

An Openness Agreement on Animal Research and Teaching in New Zealand Ensuring that the public are well informed about what animal research involves and the role it plays in the overall process of scientific discovery Learn More Caring for the Animals We Use in Research and Teaching ANZCCART is the Australian & New Zealand Council for the Care of Animals in Research and Teaching. We are located in both New Zealand and Australia . Our websites contain information for animal carers, animal ethics committee members, scientists, schools as well as other interested parties. Through these websites, we hope to further the primary goals of ANZCCART which include promoting the responsible use of animals in research and teaching, and informed discussion and debate within the community regarding these matters. When viewing our websites please be mindful that legislation and some animal welfare information will differ between our countries. Learn More Featured Initiatives Openness Agreement We support the Openness Agreement on Animal Research and Teaching for New Zealand. Read More Three Rs Resources Check out our resources covering the three Rs (replacement, reduction and refinement) in the use of animals in research and teaching. Read More Compass Training ​ This free online course covers the Australian Code and NZ Guide and welfare issues relating to animal use in research and teaching. Read More

Information for New Zealand Researchers and Tertiary Education Researchers, technicians or tertiary teachers are often directly responsible for animal welfare. The following information has been designed by ANZCCART to assist these groups when they are conducting research, testing and/or undertaking teaching involving animals. Animal ethics and legislation in New Zealand Please click to follow link for information on ethics and legislation in New Zealand . Understanding Animal Ethics Committees Please click to follow link for information on Animal Ethics Committees and the criteria for assessing applications . Assistance with statistics in designing studies with animals Appropriate research study design is an important part of reducing the numbers of animals used in research and testing. We strongly recommend the free interactive course on designing animal experiments provided by Michael Festing. Designing and reporting animal experiments ANZCCART (NZ) endorses the PREPARE and ARRIVE guidelines for the designing and reporting of animal experiments involving the use of animals. The guidelines are intended to improve the planning and reporting of research using animals – maximising information published and minimising unnecessary studies. PREPARE guidelines for planning animal experiments can be found here . ARRIVE guidelines for reporting animal experiments can be found here . The ARRIVE reporting guidelines have been endorsed by over 1,000 scientific journals including nature, and the journals of the Royal Society Te Apārangi. A 3-minute video about the PREPARE guidelines can be found here . Animal welfare Please click to follow link for information on managing pain and anaesthesia in research animals. Alternatives to using animals in research, testing, or teaching Please click to follow link for information on alternatives to using animals in research, testing, or teaching. ComPass Animal Welfare Training This free online course covers the Australian Code and NZ Guide and welfare issues relating to animal use in research and teaching. Successful completion of Phase one of the course and its quiz fulfills the mandated basic training needs of researchers and teachers using animals as well as members of Animal Ethics Committees (AEC) in Australia and NZ (except AEC members in Victoria who are required to complete the Animal Welfare Victoria training). The aim is to standardize and augment the training offered for animal users in research and teaching throughout Australasia by offering this free online interactive and resource-rich course to all who need this training. For the course link and more information . Resource bank and recommendations on best practice There are ANZCCART resources and Links to r esources from other organisations that contain information and resources about animal welfare and alternatives to using animals. If you would like to add information or resources to this database please contact us . Information updates Our regular newsletter ANZCCART News contains updates on animal welfare, legislation and alternatives to using animals. If you are doing work that has animal ethics approval you should receive this newsletter (via email). If you have not been receiving a copy of ANZCCART News please contact us . Archived editions are available here . ANZCCART Conferences ANZCCART holds an annual conference which discusses animal welfare in the context of research, testing and teaching. The conference location varies and usually is held two successive years in Australia followed by one year in New Zealand. For more details please see our conference page . ANZCCART Contacts for questions If you have any questions or concerns please feel free to contact us .

Secondary school resources for New Zealand Teachers This section contains information and resources that teachers can use in the classroom to help introduce the topic of animal research. For more information on applying for animal ethics for a teaching activity or a science project please see the “ Animal ethics in NZ schools ” section of this website. NCEA Resources for Schools ANZCCART (NZ) has supported the development of four NCEA assessment tasks that have received the Quality Assured Assessment materials trade mark (QAAM) from the NZQA for NCEA Achievement Standards (Biology 1.2, 2.2, and 3.2), which integrates biological knowledge to develop an informed response to a socio-scientific issue. The four resources are: Biology 1.2 (AS 90926) Animal research: What’s a life worth? – NCEA Level 1 – Internal Assessment Resource Biology 2.2 (AS 91154) Animal research: The best thing for human medicine and animals? – NCEA Level 2 – Internal Assessment Resource Biology 3.2 (AS 91602) Animal research: The ethics of using animals for research and teaching in New Zealand – NCEA Level 3 – Internal Assessment Resource Biology 3.2 (AS 91602) Animal research: Predator proof fences – NCEA Level 3 – Internal Assessment Resource Each of the tasks is available as a ‘ready to use’ package and contains: The achievement standard Teacher guidelines for and conditions of assessment The assessment task The assessment schedule Planning notes for teachers and suggested resources These teaching resources are not available on-line, but can be sent to teachers upon request ( contact ANZCCART NZ ). A student resource to accompany these tasks, Using Animals in Science: Student Resource, is available to download here . Caring for the animals we use in research and teaching ANZCCART has produced a resource called “Caring for the animals we use in research and teaching”. The centrepiece of this resource is a DVD which provides a series of interviews with scientists who use animals in their research. This DVD is an excellent resource for generating class discussion and debate around the use of animals in research and teaching. The research topics discussed on the DVD are: research into developing anti-cancer drugs (presented by Professor Bill Wilson); genetic causes for obesity (presented by Dr Kathy Mountjoy); the effects of pre-natal nutrition on lambs (presented by Professor Jane Harding); the use of pain relief on farms for procedures such as castration and docking of lambs’ tails (presented by Dr Craig Johnson); the effects of the gene kisspeptin on puberty and fertility (presented by Professor Allan Herbison); development of the Xcluder Pest Proof Fence which is in use at Maungatautari (presented by Dr Tim Day); legislation governing the use of animals in research and teaching (presented by Professor Don Love and Dr Sally Birdsall). The video clips from the DVD can be downloaded by teachers from the following web link . A password will be required and will be available upon request to teachers ( contact ANZCCART NZ ). A compilation of interviews on these topics, narrated by Dr Jessie Jacobsen, the 2007 MacDiarmid Young Scientist of the Year (now called the Prime Minister’s MacDiarmid Emerging Scientist of the year), is also available. Activities for the New Zealand School Curriculum A set of activities has been developed to accompany each of the interviews for Years 9-10 students. They are designed to encourage discussion about the ways in which animals are used in research, as well as having a literacy focus. Each set of activities has links to the Nature of Science strand and to relevant contextual strands in the revised New Zealand school curriculum together with suggested ways of developing relevant key competencies. If you would like a copy of the DVD, please contact ANZCCART NZ . Resource links for teachers on the use of animals in research, testing or teaching The following resources are available for teachers on the use of animals in research, testing or teaching: Alt web (resource database hosted by Johns Hopkins University) Animal ethics resources on TKI website Using animals in science , student resource (ANZCCART publication) (PDF, 2.8 MB, 22 pages) Animal research saves lives, questions and answers (ANZCCART resource) (PDF, 1.8 MB, 14 pages) Animal welfare in NZ (Ministry for Primary Industries) Culture of Care (A NAEAC guide for people working with animals in research, testing and teaching) (PDF, 393 kb, 6 pages) DEMOCS discussion game (from EdinEthics, UK website) Download Three Rs poster (ANZCCART resource) (PDF, 6.7 MB, 1 page) Introduction to statistics for research involving animals (website by Dr Michael Festing, Charted Statistician) National Animal Ethics Advisory Committee (NAEAC) website National Animal Welfare Advisory Committee (NAWAC) website NZ Association of Science Educators (NZASE) website on animal ethics SPCA New Zealand

Information on Animal Research in New Zealand for Schools It is the responsibility of everyone who uses animals to ensure that they are only used when absolutely necessary and that when they are used they are treated with care and respect. If an animal is used for research, testing or teaching the work must be conducted in line with the Three Rs (from the ideas of Russell and Burch in their 1959 book “The principles of humane experimental technique”, available through the Johns Hopkins Alt Web website): Replacement : where possible an alternative to animal testing must be used. This could include a computer model or cell culture (where animal or human cells are grown in a laboratory). Reduction : the minimum number of animals must be used to gain good experimental results. This means that experiments must be well designed and that as many experimental variables as possible are controlled (i.e. that you only change one thing in your experimental group as compared to your control group). This means that the research or test will provide quality data which can withstand statistical analysis. Refinement : the animals should not suffer. At all times the health and well-being of the animal should be a priority. As much as possible the animal should be able to live normally, free from any pain and suffering, throughout the research, teaching or testing process. ANZCCART booklets providing examples of how these principles have been applied are available here . Resources on the use of animals in research, testing or teaching for schools The following resources are available on the use of animals in research, testing or teaching: Using animals in science , student resource (ANZCCART publication 2019) (PDF, 2.8 MB, 22 pages) Animal research saves lives, questions and answers (ANZCCART resource 2013) (PDF, 1.8 MB, 14 pages) Download Three Rs poster (ANZCCART resource) (PDF, 6.7 MB, 1 page) Animal welfare in NZ (Ministry for Primary Industries) National Animal Ethics Advisory Committee (NAEAC) website National Animal Welfare Advisory Committee (NAWAC) website Alt web (resource database hosted by Johns Hopkins University) SPCA New Zealand Animal ethics resources on TKI website DEMOCs discussion game (from EdinEthics, UK Website)

Information for New Zealand Animal Ethics Committee Members The following information has been designed by ANZCCART to assist Animal Ethics Committee members in undertaking their roles in relation to animal ethics applications and animal welfare. ComPass Animal Welfare Training This free online course covers the Australian Code and NZ Guide and welfare issues relating to animal use in research and teaching. For the course link and more information . Resources and recommendations on best practice The resource bank and recommendations on best practice contains a variety of information and resources around animal welfare and alternatives to using animals. If you would like to add information or resources to this database please contact us. Information on research study design Appropriate research study design is an important part of reducing the numbers of animals used in research and testing. We strongly recommend the free interactive course on designing animal experiments provided by Dr Michael Festing. This website may be useful in improving your own understanding of appropriate research design and should be recommended viewing for those seeking animal ethics approval for projects. Information about induction onto an Animal Ethics Committee An AEC member induction information package should be provided to you when you join the committee. Produced by the National Animals Ethics Advisory Committee (NAEAC), this pack contains an overview of information relevant to serving on an AEC. If you have any concerns or you have not received your induction information pack please contact NAEAC (naeac@mpi.govt.nz). Updates on animal welfare, legislation and alternatives to using animals Our regular newsletter ANZCCART News contains updates on animal welfare, legislation and alternatives to using animals. Annual conferences on animal welfare for research, testing or teaching ANZCCART holds three-day conferences every year which discuss animal welfare in the context of research, testing or teaching. The conference location varies and alternates between Australia and New Zealand every third year. For more details please see our conference page . How to Contact ANZCCART for questions and queries If you have any questions or concerns please feel free to contact ANZCCART. Our details are listed on our contact page . Resource links for New Zealand Animal Ethics Committee Members The following resources are available for New Zealand Animal Ethics Committee Members: Alt web (resource database hosted by Johns Hopkins University) Animal welfare in NZ (Ministry for Primary Industries website) ANZCCART Conferences on animal welfare for research, testing or teaching ANZCCART Newsletter Guide to the Animal Welfare Act (Ministry for Primary Industries website) ANZCCART resource bank and recommendations on good practice SPCA New Zealand The Animal Welfare Act 1999 (Parliamentary Council Office website) The National Animal Ethics Advisory Committee (NAEAC) website The National Animal Welfare Committee (NAWAC) website Veterinarians for Animal Welfare Aotearoa (website)